Ottawa Hospital Research Institute

Research News

	New solutions needed to reduce blood loss during bladder removal surgery November 5, 2024 - "This study proves that routine use of tranexamic acid is not effective, so we need to explore other options."
	Increasing access to cutting-edge research: new initiative benefits local patients October 2, 2024 - The Ottawa Health Science Network Research Ethics Board (OHSN-REB) is spearheading an important initiative to enhance patient access to clinical trials and increase the efficiency and effectiveness of clinical research across the region.
	New pan-Canadian data and sample transfer agreement a game-changer for clinical research July 2, 2024 - “We’ve built a high-speed legal highway for researchers to use to share their data and samples.”
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	Can a blood test predict if MS attacks will come back after stopping treatment? March 15, 2024 - Some people prefer to stop immune-suppressing treatment if their disease has been stable for years, but there’s no way to know whether their symptoms will return.
	“Super-collaborator” helps patients breathe easier November 9, 2023 - Dr. Shawn Aaron is receiving The Ottawa Hospital’s Grimes Career Achievement Award for practice-changing research in COPD and other chronic lung diseases
	Will I be on dialysis forever? New calculator could help kidney disease patients June 9, 2023 - People who receive their first kidney dialysis treatment during a hospital admission often wonder if their kidneys will eventually recover, or if they will need to continue dialysis for the rest of their lives. A new calculator developed by Dr. Edwar
	New scientist profile: Dr. Joseph Shaw investigates best way to “turn off” blood thinners March 16, 2023 - Thrombosis physician Dr. Joseph Shaw knows blood thinners are great for preventing blood clots. But sometimes people taking these drugs need to be able to form blood clots again, like before a surgery, or if they start bleeding in the brain or gut.
	International team investigates cause of space anemia March 16, 2023 - Dr. Guy Trudel is leading a collaborative research project to uncover key mechanisms of spaceflight-related anemia.
	How should patients with acute heart failure be monitored? This tool can help. March 7, 2023 - A clinical decision tool used in the emergency department can improve outcomes for patients with acute heart failure, according to trial involving more than 5,000 patients, published in the New England Journal of Medicine.
	Why more patients are taking a front seat in medical research January 27, 2023 - After undergoing surgery herself, Gurlie Kidd was so interested in work on a team studying “prehabilitation” for frail patients undergoing surgery, that she got involved.
	New Research Chair in Gay Men’s Health is setting out to break down barriers to care January 27, 2023 - As both a researcher and a gay man, Dr. MacPherson knows all too well the stigma, stereotypes and misinformation that gay men often encounter in the health-care system. He has dedicated much of his career to breaking down these barriers by helping he
	People with lived experience of cancer are bringing crucial insights to studies January 11, 2023 - The early days after Gary Davis’s leukemia diagnosis were all a blur. Now cancer-free, Gary is advising our researchers on how to navigate difficult conversations about study participation with patients like himself
	New biomarker could help predict severity of COVID-19 infection October 28, 2022 - New research led by Dr. Benjamin Tsang and Taggart-Parkes postdoctoral fellow Dr. Meshach Asare-Werehene shows that a blood protein called plasma gelsolin (pGSN) could help predict which hospitalized COVID-19 patients are likely to become severely il
	Questionnaire can find people with undiagnosed asthma, COPD June 2, 2022 - A team led by Dr. Shawn Aaron developed and validated a tool published in the European Respiratory Journal that can detect undiagnosed asthma and COPD in adults with symptoms.
	The Ottawa Hospital’s push to demystify Parkinson’s disease April 29, 2022 - Parkinson’s is the second most common neurodegenerative disease after Alzheimer’s, affecting at least 100,000 Canadians. Researchers at The Ottawa Hospital are on the global stage seeking answers for patients desperately waiting for a breakthrough.
	Research sets new standard for treating latent tuberculosis in Canada March 24, 2022 - A transformational treatment for latent tuberculosis (TB) is now the standard of care in Canada, thanks to research led by The Ottawa Hospital. The Canadian Thoracic Society’s new Canadian TB Standards, released on March 24, 2022, recommend 3HP (rifa
	New CIHR grants to support an equitable pandemic recovery March 16, 2022 - Researchers at The Ottawa Hospital have been awarded four grants as part of CIHR’s Emerging COVID-19 Research Gaps and Priorities competition, which was designed to support an equitable pandemic recovery for all Canadians.
	The Ottawa Hospital Joins Michael J. Fox Foundation’s Expansion of the Parkinson’s Progression Markers Initiative (PPMI), Landmark Study toward Better Treatments and Prevention of Disease March 3, 2022 - The Ottawa Hospital aims to enroll people recently diagnosed with Parkinson’s who are not yet taking medication and individuals over age 60 with certain risk factors in the Parkinson’s Progression Markers Initiative (PPMI),
	228 clinical practices used inappropriately in Canada February 28, 2022 - A study led by Dr. Janet Squires identified 228 clinical practices in Canada that are used inappropriately, with underuse being more common than overuse.
	Study reinforces new treatment option for stroke prevention February 17, 2022 - A network meta-analysis led by Dr. Dar Dowlatshahi and neurology resident Dr. Ronda Lun found that ticagrelor is just as good as clopidogrel when combined with aspirin as a dual antiplatelet therapy.
	Getting the clot out on first try improves outcomes for basilar artery stroke patients January 21, 2022 - Pulling a clot out of the brain on the first try significantly improves outcomes for patients with basilar artery stroke, according to a study published in Stroke led by Dr. Robert Fahed. This rare kind stroke can cause death or severe disability by
	Being in space destroys more red blood cells January 14, 2022 - A world-first study has revealed how space travel can cause lower red blood cell counts, known as space anemia. Analysis of 14 astronauts showed their bodies destroyed 54 percent more red blood cells in space than they normally would on Earth, accord
	New scientist profile: Dr. Mark Canney uses big data to answer burning questions in kidney disease December 9, 2021 - As a kidney specialist with a background in epidemiology and statistics, Dr. Mark Canney is interested in the questions that most trouble his colleagues.
	Some inhaled corticosteroids for asthma, COPD safer and more effective for older adults September 29, 2021 - Study reveals important new information for physicians who prescribe inhaled corticosteroids to older patients, a common daily treatment for asthma and COPD
	A glimpse inside the mind of neurosurgery expert, Dr. Fahad Alkherayf August 18, 2021 - Dr. Fahad Alkherayf is the Director of the Clinical Research Program in the Neurosurgery Division of The Ottawa Hospital. As a neurosurgeon, he specializes in minimally invasive surgeries, which use much smaller incisions than traditional surgeries
	A conversation with Dr. Jess Fiedorowicz August 18, 2021 - Dr. Jess Fiedorowicz is shining a light on mental health through his work and research at The Ottawa Hospital. Originally from the U.S., Dr. Fiedorowicz has been at our hospital since 2020 as the Head and Chief of the Department of Mental Health.
	Motivational incentives make a difference for treating opioid use disorder June 23, 2021 - Providing incentives like free movie passes or small cash rewards to motivate people with opioid use disorder to continue opioid agonist therapy (OAT) improves retention in the treatment program, according to a systematic review led by Drs. Brian Hut
	Research study to improve patient care during pandemic March 17, 2021 - Meagan Gordon spent much of her high-risk twin pregnancy confined to a room at our hospital to keep her and her babies safe during the COVID-19 pandemic. Now, she's helping our researchers improve care.
	New scientist profile: Dr. Jess Fiedorowicz brings an interdisciplinary vision to mental health research March 10, 2021 - Dr. Jess Fiedorowicz has built his research career on bringing together specialists from different disciplines to better understand the health risks faced by people with severe mental disorders, with a focus on bipolar disorder.
	Partnering with the marginalized December 11, 2020 - To tackle health-care inequities affecting vulnerable populations, Smita Pakhalé turns to community peer researchers in a grassroots approach to epidemiological research.
	The Ottawa Hospital contributes to ‘a beautiful evolution’ in HIV research and care December 4, 2020 - In honour of World AIDS day, we take a look back at how The Ottawa Hospital played a major role in caring for patients with HIV, how it continues to lead life-saving research, and how it is transforming how HIV is managed today.
	Probing the mysteries of COVID immunity October 15, 2020 - Stop the Spread Ottawa is an initiative aimed at accelerating vaccine development against the novel coronavirus that has transformed our way of life.
	Canadian study compares COVID-19 spit test to traditional swab test September 8, 2020 - A new study led by researchers at The Ottawa Hospital, University of Ottawa and the Public Health Agency of Canada’s National Microbiology Laboratory shows that a Canadian-made spit test can detect the COVID-19 virus.
	Cannabis use in pregnancy linked to a greater risk of autism August 10, 2020 - In the largest study of its kind, researchers from The Ottawa Hospital, BORN Ontario and the University of Ottawa found that children whose mothers reported using cannabis during pregnancy were at greater risk of autism.
	Decoding the mystery of Parkinson’s disease July 10, 2020 - For more than 200 years, no one has been able to solve the Parkinson puzzle. While the exact cause of the disease remains a mystery, dedicated researchers at The Ottawa Hospital are gaining ground—determined to solve the puzzle.
	The Ottawa Hospital awarded $4.7 million for COVID-19 research from the Canadian Institutes of Health Research June 25, 2020 - Researchers at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $4.7 million from the Canadian Institutes of Health Research (CIHR) for four research projects that could transform our understanding of COVID-19 and lead
	Understanding the challenge of COVID-19 for Ottawa’s most vulnerable people June 8, 2020 - Dr. Smita Pakhale and her colleagues will harness the trust and engagement they have built with Ottawa’s most marginalized communities over the last 10 years through community-based participatory action research to examine how COVID-19 has impacted t
	How are you coping during COVID-19? April 20, 2020 - COVID-19 is changing core aspects of people’s lives in a unique manner. Social interactions, family and work are all affected. Researchers want to understand the impacts of these changes and determine what helps people cope.? They have launched a stu
	Researchers join the fight against COVID-19 April 2, 2020 - As hospitals and communities band together to fight COVID-19, researchers at The Ottawa Hospital are harnessing their unique expertise and resources to help.
	Assisted reproductive technology and heart problems: it’s (mostly) about the twins February 24, 2020 - Babies born through Assisted Reproductive Technology (ART) like in vitro fertilization have a small but significantly increased risk of being born with heart problems (2.2 percent for ART babies compared to 1.2 percent for non-ART babies). Now, a new
	More time in space linked with anemia February 19, 2020 - More astronauts are anemic after longer space flights, according to a study led by Dr. Guy Trudel. Anemia is a reduced level of red blood cells that can make people feel weak or tired.
	Dr. Jeremy Grimshaw elected into Royal Society of Canada September 10, 2019 - Dr. Jeremy Grimshaw has been elected a Fellow of the Royal Society of Canada, a group called upon to make significant and substantial contributions of knowledge, understanding, and insight through engagement with the larger society.
	Study establishes long-term risks and consequences of leg vein clot recurrence July 31, 2019 - Over 750,000 Canadians will have an unexplained vein blood clot in their lifetime, known as venous thrombosis. A collaborative study led by Dr. Marc Rodger and Faizan Khan now provides the best data yet on the long-term risks and consequences of recu
	Are we using biologic therapy properly? June 13, 2019 - The introduction of infliximab (Remicade), the first biologic therapy approved for the treatment of inflammatory bowel diseases (IBD), did not result in lower rates of hospitalizations or intestinal surgeries among patients living with IBD in Ontario
	Start discussions on end-of-life care earlier, study suggests May 15, 2019 - A study led by Dr. Kwadwo Kyeremanteng found that many patients with terminal cancer who visited the Emergency Department in 2012 within two weeks of dying in hospital did not have an advanced care plan.
	Do-not-resuscitate (DNR) and do-not-hospitalize (DNH) orders not enough to prevent potentially avoidable hospital visits: study April 15, 2019 - Do-not-resuscitate (DNR) and do-not-hospitalize (DNH) orders in long-term care homes (nursing homes) across Ontario led to reductions in rates of hospitalizations and hospital deaths, but did not eliminate these potentially inappropriate transfers, a
	Guidelines can help patients avoid unnecessary blood transfusions April 15, 2019 - Dr. Dean Fergusson played a lead role in an important set of guidelines for patient blood management published in JAMA.
	Helping evidence-based public health guidelines work in the real world April 3, 2019 - Dr. Jeremy Grimshaw played an important role in an international exercise to strengthen how the World Health Organization develops guidelines to improve public health.
	New scientist profile: Dr. Hanns Lochmüller investigates rare neuromuscular disorders March 15, 2019 - Dr. Hanns Lochmüller, a neurologist and senior scientist recently recruited to CHEO Research Institute from the U.K., has now also been appointed as an associate scientist in the Neuroscience Program at the Ottawa Hospital Research Institute.
	Researcher brings made-in-Ottawa approach to Parkinson’s care to Europe March 15, 2019 - A personalized approach for Parkinson’s care pioneered in Ottawa will soon be tested in Europe, thanks to a prestigious $2.2 M grant. This approach, called the Integrated Parkinson’s Care Network, was developed by Drs. Tiago Mestre and David Grimes.
	Patients and clinical trial experts key to upcoming made-in-Canada CAR-T clinical trial March 1, 2019 - Researchers at The Ottawa Hospital and the University of Ottawa are known around the world for their expertise in designing and leading clinical trials, and they're now applying this knowledge to create a made-in-Canada approach for CAR-T cell cl
	Flu vaccination keeps people with COPD out of the hospital January 30, 2019 - A study led by Dr. Sunita Mulpuru found that the flu vaccine was associated with a 38 percent reduction in flu-related hospitalizations among people with chronic obstructive pulmonary disease (COPD). The researchers looked at the records of 4755 Cana
	New scientist profile: Dr. Swapnil Hiremath harnesses science to bust medical myths January 29, 2019 - Dr. Swapnil Hiremath is inspired by his patients to uncover the truth behind medical dogma. For example, he played a lead role in busting the myth that contrast dye should never be used in medical imaging in people with serious kidney disease. He is
	Advances in radiation therapy improve treatment for early-stage prostate cancer January 16, 2019 - Many patients with early-stage prostate cancer now have access to shorter and more convenient courses of radiation treatment thanks in part to research at The Ottawa Hospital. The treatment, known as hypofractionated radiation therapy, delivers more
	Provincial innovation award for a computer tablet that could help stroke patients recover January 9, 2019 - Dr. Dar Dowlatshahi has been honored with the 2018 e-Health, Technology, and Monitoring Excellence Award by the Innovation Fund Provincial Oversight Committee. His team’s project “Recover Now: Mobile Tablet-based Stroke Rehabilitation in the Acute Ca
	Trio of BMJ papers to impact how clinical research is performed January 9, 2019 - Researchers at The Ottawa Hospital and the University of Ottawa played important roles in three papers recently published in The BMJ (British Medical Journal) that are expected to impact how clinical research is conducted around the world. The first
	Severe sleep apnea increases risk of irregular heartbeat December 11, 2018 - Severe sleep apnea increases the risk of hospitalization for new atrial fibrillation, or irregular heartbeat, according to a study led by Dr. Tetyana Kendzerska. The study followed more than 8,000 people who were originally free of any irregular hear
	Decision tool identifies which patients with COPD are at risk of death, serious complications December 3, 2018 - A made-in-Ottawa decision tool can help emergency physicians identify which patients with chronic obstructive pulmonary disease are at high risk of serious complications including death. The Ottawa COPD Risk Scale is better than current practice at p
	Engaging patients in research every step of the way November 28, 2018 - CMAJ's new supplement on engaging patients in health research features commentaries led by Drs. Dean Fergusson, Simon Hatcher and Christian Vaillancourt, as well as 14 other teams affiliated with Ontario’s SPOR SUPPORT Unit (OSSU). As co-Scientific D
	Dr. Jeremy Grimshaw honoured with CIHR Barer-Flood Prize for Health Services and Policy Research November 20, 2018 - Dr. Jeremy Grimshaw has been honoured with a pre-eminent career achievement award from the Canadian Institutes of Health Research (CIHR). The CIHR 2018 Barer-Flood Prize for Health Services and Policy Research recognizes Dr. Grimshaw as an exceptiona
	Study shows which stroke patients benefit most from clot-busting drug October 25, 2018 - Dr. Dar Dowlatshahi co-authored an international study that could help predict which ischemic stroke patients would benefit the most from a clot-busting drug. This kind of stroke can be treated with the drug alteplase or by running a long thin tube t
	Research project aims to get stroke survivors moving October 24, 2018 - Exercise has been proven to enhance brain repair, decrease depression, maintain cognitive function and reduce frailty in stroke survivors. However, stroke survivors don’t always have access to evidence-based exercise programs in the community. A new
	Chance encounter on a train led to an award-winning career in research October 22, 2018 - A job on the Rocky Mountaineer train took Dr. Kristin Danko to places that weren’t on the route between Vancouver and Calgary. One stop was a research lab at The Ottawa Hospital. Now she is the recipient of the Worton Researcher in Training Award fro
	Made-in-Ottawa rule helps patients with neck injuries in the emergency department October 17, 2018 - A study led by Dr. Ian Stiell found that triage nurses in the emergency department can safely use a made-in-Ottawa rule to make wait times shorter and more comfortable for patients who have neck pain after a fall or car collision. Due to a very small
	The cancer’s gone but the fear remains: psychology researchers tackle fear of cancer recurrence August 16, 2018 - A pilot study by Drs. Christina Tomei, Sophie Lebel, Christine Maheu, Monique Lefebvre, and Cheryl Harris suggests that specialized psychological services could help cancer survivors manage their fear of cancer returning. While this is a realistic fe
	Not sure if you can give good CPR? New data shows you probably can August 7, 2018 - Bystanders who come to the aid of someone whose heart has stopped are performing high-quality CPR that consistently meets the latest guidelines, according to a study led by Drs. Shannon Fernando, Christian Vaillancourt and Ian Stiell. Fifteen percen
	People with rare blood cancer live longer, healthier lives with new targeted treatment regimen August 1, 2018 - A study published in the New England Journal of Medicine, co-authored by Dr. David MacDonald, is providing hope and changing lives for people with Waldenström's macroglobulinemia. This rare form of cancer occurs in white blood cells called B cells, w
	$1.7 million to advance research on colon cancer, brain development, kidney disease and severe fluid loss July 20, 2018 - Four research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $1.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). Their projects will advance sci
	Urologists reduce unnecessary prostate cancer surgery in Eastern Ontario July 5, 2018 - A growing number of patients in Eastern Ontario are being saved from unnecessary prostate cancer surgeries, according to a study led by Dr. Luke Lavallée and Dr. Luke Witherspoon published in CMAJ Open. While prostate cancer is the most common cancer
	Researchers push for better patient engagement June 27, 2018 - Research improves patient care, and a growing movement aims to engage and involve patients in the research process from start to finish. However, little is known about what meaningful patient engagement in research looks like. To find out, Dr. Dean F
	Dr. Dean Fergusson chosen as President-Elect of international clinical trial society June 20, 2018 - Dr. Dean Fergusson was elected President-Elect of the Society for Clinical Trials. This organization works internationally to advance human health by advocating for the use of clinical trials, leading the development and dissemination of optimal meth
	Experimental stem cell therapy tested for rare lung disease April 30, 2018 - A Canadian-led research team has launched a clinical trial of an experimental stem cell therapy for pulmonary arterial hypertension. This rare and deadly disease occurs when the arteries that supply blood to the lungs become so damaged that blood can

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Aaron, Shawn MD, FRCPC	Senior Scientist (ICD)	Chronic obstructive pulmonary disease, Cystic fibrosis, Lung disease, Asthma	Clinical research
Addison, Christina PhD	Senior Scientist (CR)	Bone and joint degeneration, Cancer, Lung cancer, Lung disease, Pancreatic cancer, Prostate cancer, Breast cancer	Basic research, Clinical research, Cohort studies, Disease models, Drug development, Genetics, Imaging, Model organisms, Translational research, Molecular and cellular biology
Akbari, Ayub MD	Associate Scientist (ICD)	Kidney disease	Clinical research
Alvarez, Gonzalo MD, MPH, FRCPC	Senior Scientist (ICD)	First Nations, Inuit and Métis Health, Health in disadvantaged peoples, Infectious disease, Lung disease, Population health, Tuberculosis	Clinical research, Epidemiology, Public health
Angel, Jonathan MD, FRCPC	Senior Scientist (ICD)	HIV, Infectious disease	Basic research, Clinical research, Translational research
Ardolino, Michele PhD	Senior Scientist (CR)	Blood cancer, Brain cancer, Breast cancer, Cancer, Colorectal cancer, Head and neck cancer, Liver cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer, Skin cancer, Soft tissue sarcoma	Basic research, Cancer immunotherapy, Cell therapy, Clinical research, Disease models, Immunization, Immunotherapy, Model organisms, Molecular and cellular biology, Transgenic/knockout models, Translational research
Aucoin, Sylvie MD	Clinician Investigator (ACR)		Anesthesiology, Clinical research, Peri-operative medicine
Auer, Rebecca MD, MSc, FRCSC	Senior Scientist (CR)	Cancer, Colorectal cancer, Ovarian cancer, Pancreatic cancer	Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical research, Clinical trials, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Peri-operative medicine, Quality Improvement, Surgery, Translational research, Viral therapy
Aviv, Richard MBChB, FRCR (UK), FRCPC, dABR	Clinician Investigator (NS)	Brain and neuromuscular disease, Brain cancer, Head and neck cancer, Multiple sclerosis, Stroke, Subarachnoid hemorrhage, Traumatic brain injury, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Clinical research, Cluster randomized trials, Disease models, Health economics, Health technology, Imaging, Patient safety, Quality Improvement, Translational research
Beaulac, Julie PhD	Clinician Investigator (ICD)		Clinical research, Health promotion, Health services research, Psychology, Shared decision making
Beltran-Bless, Ana-Alicia MD	Clinician Investigator (CR)		Clinical research, Patient engagement, Pragmatic trials
Bissell, Mary Beth MSc, MD, FRCPC	Clinician Investigator (CR)	Breast cancer, Cancer, COVID-19, Population health, Women's health	Clinical research
Breau, Rodney MD	Senior Scientist (ACR)	Cancer, Kidney disease, Prostate cancer	Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Imaging, Patient decision aids, Patient engagement, Quality Improvement, Surgery, Systematic reviews, Transfusions
Bredeson, Christopher MD MSc FRCPC	Senior Clinician Investigator (CR)	Blood cancer	Clinical research, Stem cells, Transplantation
Burns, Kevin MD CM, FRCPC	Senior Scientist (ICD)	Diabetes, Kidney disease, Vascular, heart and metabolic disease	Basic research, Biomarkers, Cell therapy, Clinical research, Disease models, Extracellular vesicles / exosomes, Gene expression, Molecular and cellular biology, Regenerative medicine, Stem cells, Transgenic/knockout models, Translational research
Cameron, Bill MD FRCPC FACP FIDSA	Senior Scientist (ICD)	Chronic obstructive pulmonary disease, COVID-19, Cystic fibrosis, HIV, Infectious disease, Sexually transmitted infections, Tuberculosis	Clinical research, Epidemiology, Immunization, Immunotherapy, Pharmacology
Carrier, Marc MD, MSc, FRCPC	Senior Scientist (ICD)	Cancer, Thrombosis / thromboembolism	Clinical research, Patient engagement
Castellucci, Lana MD, FRCPC, MSc	Scientist (ICD)	Thrombosis / thromboembolism	Clinical research, Clinical trials, Cohort studies, Critical care, Patient engagement, Systematic reviews, Transfusions
Caulley, Lisa MD PhD FRCSC	Associate Scientist (ACR)	Cancer, Head and neck cancer	Clinical research, Epidemiology, Health economics, Journalology, Public health
Chakraborty, Santanu MBBS, MRCP, DMRD, FRCR, FRCP(C)	Senior Clinician Investigator (NS)	Amyotrophic lateral sclerosis, Brain cancer, Concussion, Dementia, Head and neck cancer, Multiple sclerosis, Parkinson's, Spinal cord injury, Stroke, Traumatic brain injury	Bioinformatics, Clinical research, Health economics, Health professional behaviour change, Imaging, Immunization, Patient safety, Quality Improvement, Risk assessment
Chen, Innie MD, MPH, FRCSC	Scientist (ACR)	Health equity, Population health, Pregnancy, Women's health	Clinical research, Epidemiology, Health research methods, Patient engagement, Quality Improvement, Systematic reviews
Clark, Edward MD MSc FRCPC	Associate Scientist (ACR)	Kidney disease, Septic shock	Clinical research, Clinical trials, Epidemiology
Clemons, Mark MB BS, BMedSci, MSc, MD, FRCP, FRCPC	Scientist (CR)	Breast cancer, Cancer	Basic research, Clinical research, Clinical trials, Health research methods, Knowledge translation and implementation research
Cooper, Curtis MD, FRCPC	Scientist (ICD)	COVID-19, Hepatitis C, HIV, Infectious disease, Influenza	Clinical research, Immunization
Corrales Medina, Vicente MD	Clinician Investigator (ICD)	Pneumonia, Vascular, heart and metabolic disease	Clinical research
Crawley, Angela Ph.D.	Senior Scientist (ICD)	Cancer, COVID-19, Hepatitis C, HIV, Infectious disease, Liver cancer, Liver disease	Basic research, Cancer immunotherapy, Clinical research, Disease models, Immunization, Immunotherapy, Molecular and cellular biology, RNA sequencing, Translational research
Dennis, Kristopher MD FRCPC PhD	Clinician Investigator (CR)	Cancer, Colorectal cancer, First Nations, Inuit and Métis Health, Gastric cancer, Liver cancer, Pain, Pancreatic cancer	Behaviour, Biomarkers, Clinical research, Clinical trials, Cohort studies, Health professional behaviour change, Health services research, Palliative care, Pragmatic trials, Qualitative methods, Quality Improvement, Systematic reviews
Duffett, Lisa MD	Associate Scientist (ICD)	Thrombosis / thromboembolism	Clinical research, Clinical trials, Epidemiology
El-Chaar, Darine MD, FRCSC, Msc	Scientist (ICD)	Autoimmune disease, COVID-19, Diabetes, Infectious disease, Inflammatory bowel syndrome, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health research methods, Health services research, Public health, Qualitative methods, Quality Improvement, Systematic reviews
English, Shane MD	Senior Scientist (ACR)	COVID-19, Septic shock, Subarachnoid hemorrhage, Traumatic brain injury	Clinical research, Critical care, Patient engagement
Fadda, Giulia MD	Associate Scientist (NS)	Autoimmune diseases of the nervous system, Multiple sclerosis	Bioinformatics, Biomarkers, Biostatistics, Clinical research, Imaging, Immunotherapy, Molecular and cellular biology, Patient engagement, Translational research
Fahed, Robert MD MSc	Associate Scientist (NS)	Stroke, Subarachnoid hemorrhage	Biostatistics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Epidemiology, Imaging, Pragmatic trials, Quality Improvement, Shared decision making, Systematic reviews
Fergusson, Dean PhD, MHA, FCAHS	Program Director and Senior Scientist (MIR)	Cancer, COVID-19, Kidney disease, Septic shock, Vascular, heart and metabolic disease	Clinical trials, Health services research, Health technology, Patient engagement, Pragmatic trials, Surveys, Translational research, Biostatistics, Clinical research, Cluster randomized trials, Cohort studies, Critical care, Health research methods, Qualitative methods, Quality Improvement, Systematic reviews, Transfusions
Fiedorowicz, Jess MD, PhD	Scientist (NS)	Bipolar, Mental health, Suicide, Vascular, heart and metabolic disease	Clinical research, Epidemiology
Freedman, Mark HBSc, MSc, MD, CSPQ, FAAN, FRCPC	Senior Scientist (NS)	Multiple sclerosis	Cell therapy, Clinical research, Regenerative medicine, Clinical trials
Gaudet, Laura MD, MSc	Affiliate Investigator (ACR)	Newborn and child health, Pregnancy, Women's health	Clinical research
Gilbert, Sebastien MD FRCSC	Clinician Investigator (ACR)	Cancer, Gastric cancer, Gastrointestinal disease, Gastrointestinal stromal tumours (GIST), Lung cancer, Lung disease	Artificial intelligence and data science, Clinical research, Epidemiology, Health technology, Quality Improvement
Grimes, David MD, FRCPC	Associate Scientist (NS)	Huntington's, Parkinson's	Clinical research, Clinical trials, Patient decision aids
Hatcher, Simon BSc MBBS MMedSc MD FRCPC FRANZCP MRCPsych	Scientist (NS)	Anxiety, Brain and neuromuscular disease, COVID-19, First Nations, Inuit and Métis Health, Health equity, Mental health, Traumatic brain injury, Depression, Health in disadvantaged peoples, Suicide	Clinical research, Digital and mobile health, Health economics, Health professional behaviour change, Health research methods, Health services research, Health technology, Knowledge translation and implementation research, Patient engagement, Prevention, Public health, Qualitative methods, Clinical trials, Cluster randomized trials, Epidemiology, Psychology, Systematic reviews
Hiremath, Swapnil MD, MPH, FASN	Associate Scientist (ICD)	Diabetes, Health in older peoples, Heart disease, Hypertension, Kidney disease, Population health, Vascular, heart and metabolic disease	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health services research, Imaging, Pharmacology, Pragmatic trials, Public health, Quality Improvement, Systematic reviews
Hundemer, Gregory MD, MPH	Associate Scientist (ICD)	Heart disease, Hypertension, Kidney disease, Vascular, heart and metabolic disease	Biomarkers, Clinical research, Cohort studies
Hutton, Brian MSc, PhD	Senior Scientist (MIR)	Addiction, Anxiety, Breast cancer, Depression, Health equity, Health in disadvantaged peoples, Maternal and fetal health, Mental health, Population health, Suicide, Cancer	Clinical research, Cohort studies, Epidemiology, Health research methods, Health services research, Patient safety, Public health, Rapid reviews, Biostatistics, Clinical trials, Systematic reviews
Kendzerska, Tetyana MD, PhD	Associate Scientist (ICD)	Aging, Chronic obstructive pulmonary disease, Heart disease, Lung disease, Population health, Women's health	Biostatistics, Clinical research, Cohort studies, Epidemiology, Health research methods, Health services research, Systematic reviews
Knoll, Gregory MD, MSc, FRCPC	Senior Scientist (ICD)	Kidney disease	Clinical research, Transplantation
Kwok, Edmund MD MHA MSc FRCPC	Clinician Investigator (ACR)		Clinical research, Critical care, Emergency medicine, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Patient safety, Pragmatic trials, Qualitative methods, Quality Improvement, Rapid reviews, Systematic reviews
Lalu, Manoj MD, PhD, FRCPC	Scientist (ACR)	Blood cancer, COVID-19, Heart disease, Stroke, Vascular, heart and metabolic disease	Anesthesiology, Basic research, Cell therapy, Clinical research, Clinical trials, Disease models, Health research methods, Model organisms, Patient engagement, Regenerative medicine, Stem cells, Translational research
Lavallee, Luke MDCM, MSc, FRCSC	Associate Scientist (ACR)	Cancer, Kidney disease, Population health, Prostate cancer	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health economics, Health professional behaviour change, Imaging, Knowledge translation and implementation research, Patient decision aids, Quality Improvement, Surgery, Systematic reviews
Le Gal, Gregoire MD, PhD	Senior Scientist (ICD)	Thrombosis / thromboembolism	Clinical decision rules, Clinical research, Clinical trials, Epidemiology, Patient engagement, Peri-operative medicine
Lemaire, Edward PhD	Affiliate Investigator (MIR)	Aging, Bone and joint degeneration, Bone and joint injuries, Concussion, Global health, Musculoskeletal conditions, Spinal cord injury, Traumatic brain injury, Traumatic injuries	Big data, Clinical research, Clinical trials, Health research methods, Quality Improvement, Rehabilitation, Health technology
Liu, Johné PhD	Senior Scientist (ICD)	Aging, Cancer, Infertility, Maternal and fetal health, Pregnancy, Women's health	Basic research, Clinical research, Clinical trials, Disease models, Drug development, Translational research
Martel, Guillaume MD, MSc (Epi), FRCSC, FACS	Scientist (ACR)	Anemia, Bleeding disorders, Colorectal cancer, Liver cancer, Liver disease, Pancreatic cancer	Anesthesiology, Clinical research, Clinical trials, Peri-operative medicine, Surgery, Systematic reviews, Transfusions
McInnes, Matthew MD PhD FRCPC	Scientist (MIR)	Cancer, Liver cancer	Clinical research, Epidemiology, Health research methods, Imaging, Journalology, Systematic reviews
McIntyre, Lauralyn MD, MHSc, FRCPC	Senior Scientist (ACR)	Septic shock	Cell therapy, Clinical research, Clinical trials, Critical care, Patient engagement, Pragmatic trials, Stem cells, Transfusions, Translational research
McIsaac, Daniel MD, MPH, FRCPC	Scientist (ACR)	Aging, Frailty, Health in older peoples, Pain, Population health	Anesthesiology, Artificial intelligence and data science, Big data, Biostatistics, Clinical research, Clinical trials, Cohort studies, Digital and mobile health, Epidemiology, Health services research, Patient engagement, Peri-operative medicine, Public health, Quality Improvement, Risk assessment, Surgery, Systematic reviews
Mitchell, Simeon MD CM, MScHQ, FRCPC	Clinician Investigator (ACR)		Clinical research, Emergency medicine, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Patient engagement, Patient safety, Quality Improvement
Moore, Gregory MD, FRCPC	Clinician Investigator (ACR)	Newborn and child health	Clinical research, Knowledge translation and implementation research, Patient decision aids, Qualitative methods, Quality Improvement, Shared decision making, Systematic reviews
Morgan, Scott MD, MSc, FRCPC	Clinician Investigator (CR)	Bladder cancer, Breast cancer, Cancer, Prostate cancer	Biomarkers, Clinical research, Clinical trials, Cohort studies, Imaging, Systematic reviews
Murthy, Sanjay MD, FRCPC	Scientist (ICD)	Colorectal cancer, Crohn's, Gastrointestinal disease, Inflammatory bowel syndrome	Clinical decision rules, Clinical research, Cohort studies, Epidemiology, Health economics, Health services research
Nair, Vimoj MBBS MD MSc FRCPC	Clinician Investigator (CR)	Blood cancer, Brain cancer, Colorectal cancer, Gastric cancer, Liver cancer, Pancreatic cancer	Artificial intelligence and data science, Biostatistics, Cancer biotherapeutics, Clinical research, Clinical trials, Health technology, Imaging, Pragmatic trials, Quality Improvement, Translational research
Nessim, Carolyn MD, MSc, FRCSC, FACS	Clinician Investigator (CR)	Cancer, Colorectal cancer, Gastric cancer, Gastrointestinal disease, Gastrointestinal stromal tumours (GIST), Soft tissue sarcoma, Skin cancer	Biomarkers, Clinical trials, Gene expression, Immunotherapy, Surgery, Translational research, Viral therapy, Clinical research, Immunotherapy
Pakhale, Smita MD, FRCPC, MSc (Epi & Biostat)	Senior Scientist (ICD)	COVID-19, First Nations, Inuit and Métis Health, Health equity, Health in disadvantaged peoples, Lung disease, Sickle cell anemia	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health economics, Health promotion, Health services research, Patient engagement, Pragmatic trials, Public health, Quality Improvement
Poulin, Patricia C. Psych.	Associate Scientist (NS)	Addiction, Anxiety, Cancer, Chronic pain, Depression, Health equity, Musculoskeletal conditions, Pain	Anesthesiology, Behaviour, Biomarkers, Clinical research, Clinical trials, Emergency medicine, Epidemiology, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Palliative care, Patient decision aids, Patient safety, Peri-operative medicine, Pragmatic trials, Psychology, Qualitative methods, Quality Improvement, Systematic reviews
Ramsay, Timothy PhD	Senior Scientist (MIR)	Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury	Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Rodger, Marc MD	Senior Scientist Affiliate (ACR)	Pregnancy, Thrombosis / thromboembolism, Women's health	Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Epidemiology, Systematic reviews
Sabloff, Mitchell MSc, MDCM, FRCPC	Clinician Investigator (CR)	Blood cancer	Biomarkers, Clinical research, Clinical trials, Translational research
Santos, Marlise MD (FRCPC), MSc, MPH	Clinician Investigator (NS)	Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Schramm, David MD SM FRCSC FACS	Associate Scientist (ACR)	Cochlear implantation, Hearing loss	Biostatistics, Clinical research, Clinical trials, Epidemiology, Neuro-stimulation, Patient safety, Quality Improvement, Surgery, Systematic reviews
Shaw, Joseph MD MSc FRCPC DRCPSC	Associate Scientist (ICD)	Cancer, Thrombosis / thromboembolism	Biomarkers, Clinical research, Epidemiology, Peri-operative medicine, Pharmacology
Siegal, Deborah MD MSc FRCPC	Scientist (ICD)		Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Systematic reviews
Solmi, Marco MD, PhD, Psychiatrist	Clinician Investigator (NS)	Addiction, Anxiety, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Dementia, Depression, Mental health, Schizophrenia, Suicide	Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health research methods, Neuro-stimulation, Pharmacology, Pragmatic trials, Surveys, Systematic reviews
Srikanthan, Amirrtha MD, MHSc, FRCPC, DRCPSC (AYA Oncology)	Clinician Investigator (CR)	Breast cancer, Cancer, Gastrointestinal stromal tumours (GIST), Soft tissue sarcoma	Clinical research, Health promotion, Patient engagement, Surveys
Stacey, Dawn RN, PhD, CON(C)	Senior Scientist (MIR)		Clinical research, Clinical trials, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient decision aids, Patient engagement, Qualitative methods, Quality Improvement, Shared decision making, Surveys, Systematic reviews
Thavorn, Kednapa BPharm, MPharm, PhD	Senior Scientist (MIR)	Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision	Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews
Thiruganasambandamoorthy, Venkatesh MBBS, CCFP-EM, MSc	Senior Scientist (ACR)	Cardiac arrest, COVID-19, Heart disease, Vascular, heart and metabolic disease	Artificial intelligence and data science, Clinical decision rules, Clinical research, Emergency medicine, Epidemiology, Health services research
Tsai, Eve MD, PhD, FRCSC, CIP	Associate Scientist (NS)	Brain and neuromuscular disease, Cancer, Spinal cord injury	Biomaterials, Clinical research, Clinical trials, Imaging, Molecular and cellular biology, Regenerative medicine, Stem cells, Translational research
Tugwell, Peter O.C., MD, FRCPC	Senior Scientist (MIR)	Arthritis, Global health, Population health	Clinical research, Epidemiology, Knowledge translation and implementation research, Patient engagement, Public health, Systematic reviews
Vaillancourt, Christian MD, MSc, FRCPC, CSPQ	Senior Scientist (ACR)	Cardiac arrest, Heart disease, Population health, Spinal cord injury, Traumatic brain injury, Traumatic injuries	Clinical decision rules, Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Critical care, Emergency medicine, Epidemiology, Health economics, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Public health, Quality Improvement, Surveys, Systematic reviews
Walker, Lisa PhD, C.Psych	Clinician Investigator (NS)	Anxiety, Autoimmune disease, Autoimmune diseases of the nervous system, Brain and neuromuscular disease, Dementia, Depression, Mental health, Multiple sclerosis	Behaviour, Biomarkers, Clinical research, Exercise, Imaging, Psychology, Psychometrics, Rehabilitation, Stem cells, Systematic reviews, Translational research
Walker, Mark MD, FRCPC, MSc, MScHCM	Senior Scientist (ACR)	Global health, Health equity, Infertility, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health	Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health economics, Health promotion, Health research methods, Health services research, Knowledge translation and implementation research, Pragmatic trials, Prevention, Public health, Quality Improvement, Rapid reviews, Risk assessment, Surveys, Systematic reviews
Warman Chardon, Jodi MD, PhD FRCPC (Neurology)	Associate Scientist (NS)	Amyotrophic lateral sclerosis, Genetic myopathy, Muscular dystrophy, Neuromuscular disease, Spinal muscular atrophy, Stiff person syndrome	Artificial intelligence and data science, Clinical research, Clinical trials, Exome sequencing analysis, Genetics, Imaging, MRI muscle imaging, Next generation sequencing, RNA sequencing, Genetics
Wells, Philip MD, FRCPC, MSc	Senior Scientist (ICD)	Thrombosis / thromboembolism	Artificial intelligence and data science, Clinical research
Wilson, Kumanan MD, MSc, FRCPC	Senior Scientist (MIR)	COVID-19, Global health, Infectious disease, Newborn and child health, Population health	Artificial intelligence and data science, Big data, Biomarkers, Clinical research, Digital and mobile health, Epidemiology, Health services research, Health technology, Immunization, Public health, Transfusions, Translational research
Woulfe, John PhD, MD	Associate Scientist (NS)	Brain and neuromuscular disease, Brain cancer, Cancer, Parkinson's	Basic research, Clinical research, Translational research
Yadav, Krishan MD, MSc, FRCPC	Associate Scientist (ACR)	Infectious disease, Skin disorders	Clinical research, Emergency medicine
Zimmerman, Deborah MD	Scientist (ICD)	Frailty, Kidney disease	Clinical research, Clinical trials, Cohort studies, Epidemiology, Quality Improvement, Systematic reviews