Prostate cancer

Research News


Hormone therapy after prostate cancer surgery improves survival for some patients Hormone therapy after prostate cancer surgery improves survival for some patients
November 27, 2024 - “These results suggest that some patients should be offered hormone therapy after surgery based on how likely it is that their cancer will spread."
Earlier use of bone-strengthening agents could benefit people with prostate cancer Earlier use of bone-strengthening agents could benefit people with prostate cancer
September 20, 2024 - “These bone-strengthening agents can decrease fracture rates and the need for radiation. We hope that this study will lead to earlier, more pro-active adoption.”
Researchers at The Ottawa Hospital awarded 14 CIHR grants worth more than $10 million Researchers at The Ottawa Hospital awarded 14 CIHR grants worth more than $10 million
July 18, 2024 - “Success at CIHR underscores the creativity, dedication and collaboration of our researchers and their teams. Funding for these innovative projects paves the way for groundbreaking advancement in biomedical sciences, improved patient care and progres
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Addison, Christina
PhD
Senior Scientist
(CR)
Bone and joint degeneration, Cancer, Lung cancer, Lung disease, Pancreatic cancer, Prostate cancer, Breast cancer Basic research, Clinical research, Cohort studies, Disease models, Drug development, Genetics, Imaging, Model organisms, Translational research, Molecular and cellular biology
Ardolino, Michele
PhD
Senior Scientist
(CR)
Blood cancer, Brain cancer, Breast cancer, Cancer, Colorectal cancer, Head and neck cancer, Liver cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer, Skin cancer, Soft tissue sarcoma Basic research, Cancer immunotherapy, Cell therapy, Clinical research, Disease models, Immunization, Immunotherapy, Model organisms, Molecular and cellular biology, Transgenic/knockout models, Translational research
Breau, Rodney
MD
Senior Scientist
(ACR)
Cancer, Kidney disease, Prostate cancer Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Imaging, Patient decision aids, Patient engagement, Quality Improvement, Surgery, Systematic reviews, Transfusions
Lavallee, Luke
MDCM, MSc, FRCSC
Associate Scientist
(ACR)
Cancer, Kidney disease, Population health, Prostate cancer Clinical research, Clinical trials, Cohort studies, Epidemiology, Health economics, Health professional behaviour change, Imaging, Knowledge translation and implementation research, Patient decision aids, Quality Improvement, Surgery, Systematic reviews
Morgan, Scott
MD, MSc, FRCPC
Clinician Investigator
(CR)
Bladder cancer, Breast cancer, Cancer, Prostate cancer Biomarkers, Clinical research, Clinical trials, Cohort studies, Imaging, Systematic reviews


Related Resources

Search for clinical trials at The Ottawa Hospital related to this disease or condition.



Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "Prostate cancer” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

NCTTitleConditionStatusContact
NCT03127631A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients (NCT03127631)Prostate Cancer, Cardiovascular DiseaseRECRUITING 
NCT03936127Comparison of a Novel Transperineal Targeted Fusion Biopsy System to Conventional Transrectal Targeted Fusion Biopsy (NCT03936127)Prostate CancerRECRUITINGnschieda@toh.ca; baschwarz@toh.ca
NCT04812366Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer (NCT04812366)Prostate CancerRECRUITING 
NCT05169112Impact of Hormonal Therapy on Prostate Cancer Recurrence After Radical Prostatectomy (NCT05169112)Prostate CancerRECRUITING 
NCT03151629International Registry for Men With Advanced Prostate Cancer (IRONMAN) (NCT03151629)Prostate CancerRECRUITING 
NCT02960087Phase II High Dose Brachytherapy and Low Dose Rate Brachytherapy as Monotherapy in Localized Prostate Cancer (NCT02960087)Prostate CarcinomaRECRUITING 
NCT03718260PSMA-PET Registry for Recurrent Prostate Cancer (NCT03718260)Recurrent Prostate CancerRECRUITING 
NCT06136624Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003) (NCT06136624)Prostate Cancer MetastaticRECRUITING 
NCT05946213Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer (NCT05946213)Stage III Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8RECRUITING 
NCT04513717Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial (NCT04513717)Metastatic Malignant Neoplasm in the Bone, Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8RECRUITING 


Publications

The following research publications are pulled from PubMed using the search terms "Prostate cancer" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Randomized Phase II Study of Durvalumab with or without Tremelimumab in Patients with Metastatic Castration Resistant Prostate Cancer.
2024-11-13

Surgical Management of Genitourinary Cancer Liver Metastases.
2024-11-13

Adiposity and Muscle Strength in Men With Prostate Cancer and Cardiovascular Outcomes.
2024-10-31

Practice patterns and predictors of treatment intensification in patients with metastatic castration-sensitive prostate cancer.
2024-10-29

Drug Interactions between Androgen Receptor Axis-Targeted Therapies and Antithrombotic Therapies in Prostate Cancer: Delphi Consensus.
2024-10-16

Prior Local Therapy and First-Line Apalutamide in Patients With Nonmetastatic Castration-Resistant Prostate Cancer: A Secondary Analysis of the SPARTAN Randomized Clinical Trial.
2024-10-15

Metabolic, cardiac, and bone health testing in patients with prostate cancer on androgen-deprivation therapy: A population-based assessment of adherence to therapeutic monitoring guidelines.
2024-10-13

Testosterone Recovery Following Androgen Suppression and Prostate Radiotherapy (TRANSPORT): A Pooled Analysis of Five Randomized Trials from the Meta-Analysis of Randomized Trials in Cancer of the Prostate (MARCAP) Consortium.
2024-09-21

Effect of concomitant medications on treatment response and survival in non-metastatic castrate resistant prostate cancer: Exploratory analysis of the SPARTAN trial.
2024-09-08

Case report of a patient with an intraosseous meningioma presenting as possible metastasis from prostate cancer: Diagnostic dilemma and review of literature.
2024-09-04

View more on PubMed