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Stroke

The Ottawa Hospital has one of the strongest stroke research programs in the country, thanks to outstanding basic and clinical scientists, and its close relationships with the University of Ottawa and other associated organizations working to improve our treatment of stroke, such as the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery.

The Ottawa Stroke Program at The Ottawa Hospital is bolstered by collaborative working relationships among more than 100 researchers associated with the University of Ottawa Brain and Mind Research Institute. Stroke research at The Ottawa Hospital spans the full spectrum from basic science to clinical research to knowledge translation.

Research News


New Canada Research Chairs to advance regenerative medicine, thrombosis and stroke research at The Ottawa Hospital New Canada Research Chairs to advance regenerative medicine, thrombosis and stroke research at The Ottawa Hospital
November 14, 2024 - The federal government announced a new round of Canada Research Chairs this week, including three based at The Ottawa Hospital.
New scientist profile: Dr. Vignan Yogendrakumar aims to improve stroke care with next-generation therapies New scientist profile: Dr. Vignan Yogendrakumar aims to improve stroke care with next-generation therapies
October 22, 2024 - “My goal is to be able to offer as many patients as possible stroke treatments that will let them go home disability-free."
‘Stroke in a dish’ reveals new recipe for brain repair ‘Stroke in a dish’ reveals new recipe for brain repair
October 18, 2024 - Researchers at The Ottawa Hospital and the University of Ottawa have found a new way to create neurons – a discovery that could be a major step forward in developing treatments for stroke and traumatic brain injury.
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Albert, Paul
PhD
Senior Scientist
(NS)
Mental health, Vascular cognitive impairment, Anxiety, Depression, Intellectual disabilities, Parkinson's, Schizophrenia, Stroke, Suicide Basic research, Epigenetics, Exercise, Gene expression, Translational research, Disease models, Epigenetics, Genetics, Imaging, Molecular and cellular biology, Optogenetics, Transgenic/knockout models
Austin, Michael
MD, FRCPC, DRCPSC (PTM)
Clinician Investigator
(ACR)
Asthma, Cardiac arrest, Chronic obstructive pulmonary disease, Diabetes, Pain, Population health, Stroke Clinical decision rules, Clinical trials, Cluster randomized trials, Cohort studies, Critical care, Emergency medicine, Palliative care, Risk assessment
Aviv, Richard
MBChB, FRCR (UK), FRCPC, dABR
Clinician Investigator
(NS)
Brain and neuromuscular disease, Brain cancer, Head and neck cancer, Multiple sclerosis, Stroke, Subarachnoid hemorrhage, Traumatic brain injury, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Clinical research, Cluster randomized trials, Disease models, Health economics, Health technology, Imaging, Patient safety, Quality Improvement, Translational research
Campbell, Mark
MD, MSc
Clinician Investigator
(RM)
Bone and joint degeneration, Musculoskeletal conditions, Stroke Basic research, Regenerative medicine, Rehabilitation, Translational research
Chakraborty, Santanu
MBBS, MRCP, DMRD, FRCR, FRCP(C)
Senior Clinician Investigator
(NS)
Amyotrophic lateral sclerosis, Brain cancer, Concussion, Dementia, Head and neck cancer, Multiple sclerosis, Parkinson's, Spinal cord injury, Stroke, Traumatic brain injury Bioinformatics, Clinical research, Health economics, Health professional behaviour change, Imaging, Immunization, Patient safety, Quality Improvement, Risk assessment
Chen, Hsiao-Huei
PhD
Senior Scientist
(NS)
Aging, Autism, Dementia, Depression, Heart disease, Maternal and fetal health, Mental health, Tourette's, Alzheimer's, Alzheimer's, Anxiety, Diabetes, Obesity, Schizophrenia, Stroke, Vascular, heart and metabolic disease Disease models, Drug development, Gene expression, Neuro-stimulation, Optogenetics, Transgenic/knockout models, Basic research, Molecular and cellular biology, Translational research
Dowlatshahi, Dariush
MD PhD FRCP(C)
Senior Scientist
(NS)
Subarachnoid hemorrhage, Stroke Clinical trials, Digital and mobile health, Rehabilitation, Epidemiology
Fahed, Robert
MD MSc
Associate Scientist
(NS)
Stroke, Subarachnoid hemorrhage Biostatistics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Epidemiology, Imaging, Pragmatic trials, Quality Improvement, Shared decision making, Systematic reviews
Finestone, Hillel
MD, FRCPC
Clinician Investigator
(ICD)
Chronic pain, Musculoskeletal conditions, Pain, Stroke Rehabilitation
Hakim, Antoine
O.C., MD, PhD, FRCPC
Senior Scientist Emeritus
(NS)
Brain and neuromuscular disease, Dementia, Stroke, Vascular cognitive impairment
Lacoste, Baptiste
PhD
Senior Scientist
(NS)
Stroke, Vascular cognitive impairment, Autism Basic research, Disease models, Gene expression, Genomics, Stem cells, Genetics, Imaging, Model organisms, Molecular and cellular biology, Transgenic/knockout models
Lalu, Manoj
MD, PhD, FRCPC
Scientist
(ACR)
Blood cancer, COVID-19, Heart disease, Stroke, Vascular, heart and metabolic disease Anesthesiology, Basic research, Cell therapy, Clinical research, Clinical trials, Disease models, Health research methods, Model organisms, Patient engagement, Regenerative medicine, Stem cells, Translational research
Manuel, Douglas
MD, MSc, FRCPC
Senior Scientist
(MIR)
Aging, Alzheimer's, Cancer, COVID-19, Dementia, Diabetes, Frailty, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, Immigrant and refugee health, Infectious disease, Obesity, Parkinson's, Population health, Stroke, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Big data, Bioinformatics, Biostatistics, Digital and mobile health, Epidemiology, Health research methods, Health services research, Prevention, Public health
Perry, Jeffrey
MD, MSc, CCFP-EM
Senior Scientist
(ACR)
Stroke, Subarachnoid hemorrhage Clinical decision rules, Emergency medicine
Picketts, David
Ph.D.
Senior Scientist
(RM)
Autism, Brain and neuromuscular disease, Intellectual disabilities, Multiple sclerosis, Stroke, Vision Basic research, Disease models, Epigenetics, Molecular and cellular biology, Regenerative medicine, Stem cells, Transgenic/knockout models
Puac Polanco, Paulo
MD
Clinician Investigator
(NS)
Brain cancer, Head and neck cancer, Stroke Imaging
Santos, Marlise
MD (FRCPC), MSc, MPH
Clinician Investigator
(NS)
Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Shamy, Michel
MD MA FRCPC
Scientist
(NS)
Stroke Clinical trials, Imaging
Thavorn, Kednapa
BPharm, MPharm, PhD
Senior Scientist
(MIR)
Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews
Thornhill, Rebecca
PhD
Clinician Investigator
(MIR)
Cancer, Heart disease, Stroke, Vascular, heart and metabolic disease Artificial intelligence and data science, Biomarkers, Biostatistics, Imaging, Patient safety
Tiberi, Mario
PhD
Senior Scientist
(NS)
Parkinson's, Schizophrenia, Stroke Basic research, Drug development, Molecular and cellular biology, Proteomics, Translational research
Wang, Jing
Ph.D.
Senior Scientist
(RM)
Alzheimer's, Multiple sclerosis, Stroke Cell therapy, Disease models, Epigenetics, Imaging, Molecular and cellular biology, Regenerative medicine, Stem cells, Transgenic/knockout models
Wang, Xiang
Pharm.D, MSc, ACPR
Clinician Investigator
(ICD)
Cancer, Heart disease, Population health, Stroke, Thrombosis / thromboembolism Health services research
Yogendrakumar, Vignan
MD, PhD, FRCPC
Associate Scientist
(NS)
Stroke Biomarkers, Clinical trials, Cluster randomized trials, Cohort studies, Imaging, Pragmatic trials, Translational research






Publications

The following research publications are pulled from PubMed using the search terms "Stroke" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Consent-Related Outcomes in the Alteplase Compared to Tenecteplase Trial.
2024-11-13

From 'strong recommendation' to practice: A pre-test post-test study examining adherence to stroke guidelines for fever, hyperglycaemia, and swallowing (FeSS) management post-stroke.
2024-11-12

Anticoagulation for Patients with Atrial Fibrillation Receiving Dialysis: A Pilot Randomized Controlled Trial.
2024-11-04

Adiposity and Muscle Strength in Men With Prostate Cancer and Cardiovascular Outcomes.
2024-10-31

Internal Carotid Arteritis Associated with Sinusitis in a Child: Potential Benefit of Corticosteroids.
2024-10-25

Single-cell profiling of brain pericyte heterogeneity following ischemic stroke unveils distinct pericyte subtype-targeted neural reprogramming potential and its underlying mechanisms.
2024-10-21

Evaluating the Safety and Efficacy of Telemedicine Physician Assessments on a Mobile Stroke Unit: Protocol for a Prospective Open-Label Blinded End-Point Randomized Controlled Trial.
2024-10-19

Advance Consent for Participation in Acute Stroke Trials: A Focus Group Study with People with Lived Experience of Stroke.
2024-10-15

Endovascular treatment versus medical management for basilar artery occlusion with low-to-moderate symptoms (National Institutes of Health Stroke Scale < 10).
2024-10-14

A systematic review and meta-analysis of outcomes associated with development of surgical site infection after lower-limb revascularization surgery.
2024-10-04

View more on PubMed