Ottawa Hospital Research Institute

Research News

	Can AI predict major bleeds from blood thinners? May 28, 2024 - “More research is needed before we can use AI tools in the clinic to predict bleeding risk, but this proof-of-concept study shows they hold great promise.”
	Made-in-Ottawa AI tool could help critically ill patients February 1, 2024 - An innovative tool developed by researchers at The Ottawa Hospital is closer to helping critically ill patients following its approval by Health Canada.
	New scientist profile: Dr. David Cook surveys cellular diversity in ovarian cancer to find better treatments January 26, 2024 - “In addition to helping patients with ovarian cancer, I’m fascinated by the science of this disease, and how much we still have to learn."
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	New scientist profile: AI expert Dr. Arya Rahgozar links math with medicine September 1, 2023 - When doctors explain a problem they’re facing to Dr. Arya Rahgozar, he often thinks “I have just the tool for this in my toolbox.” For over 20 years he’s been using his data science toolbox to solve problems in banking, marketing, supply chains and h
	New scientist profile: Dr. Ayub Akbari wants to predict when patients will need dialysis July 20, 2023 - Nephrologist Dr. Ayub Akbari does his best to prepare patients with advanced chronic kidney disease for the day when their kidneys fail and they need dialysis. Unfortunately, for many patients there’s no way to know when that will happen.
	New online calculator predicts risk of developing kidney disease January 18, 2023 - Researchers at The Ottawa Hospital have developed and validated an online calculator that can estimate a person’s risk of developing chronic kidney disease. The method used to develop the tool was published in the Clinical Journal of the American Soc
	New scientist profile: Dr. Gauruv Bose aims to use AI and big data to predict the course of MS January 18, 2023 - Neurologist Dr. Gauruv Bose wants a crystal ball to see the future of his patients with multiple sclerosis (MS).
	How big data helps the big picture: Meet Dr. Alan Forster December 7, 2022 - Twenty years ago, Dr. Alan Forster was working at Harvard when he decided to join the team at The Ottawa Hospital. While other hospitals were focused on chasing the latest technology, our hospital was focused on whether that same cutting-edge technol
	Predicting Parkinson’s: mathematical model could help with earlier diagnosis and treatment September 23, 2022 - An innovative mathematical model developed by researchers at The Ottawa Hospital could one day help with the prevention and early treatment of Parkinson’s disease.
	Ottawa-led team develops AI-enabled model to diagnose birth defect in fetal ultrasound images July 14, 2022 - Artificial intelligence is poised to play a truly transformative role in global health care. The convergence of medicine and AI might eventually prove to be more impactful than the unraveling of the genome.
	New TD Artificial Intelligence in Medicine (AIM) Hub to transform healthcare in Ottawa and around the world March 1, 2022 - Through a $2-million donation from TD Bank Group (TD), The Ottawa Hospital will create the new TD Artificial Intelligence in Medicine (AIM) Hub that will accelerate the development and use of artificial intelligence (AI) in healthcare.
	Melding mind and machine: Ottawa trial could lead to new technologies to help people with paralysis June 16, 2021 - Researchers at The Ottawa Hospital and the University of Ottawa are launching a world-first clinical trial that could lead to a new kind of brain computer interface, paving the way for advanced technologies to help people with paralysis.
	Harnessing artificial intelligence and nanophotonics to fight ovarian cancer May 12, 2021 - Researchers from The Ottawa Hospital and the University of Ottawa have been awarded $150,000 from the Canadian Cancer Society, the Canadian Institutes of Health Research and the Brain Canada Foundation to harness artificial intelligence and nanophoto
	TOHAMO awards $1.2M for COVID-19 research projects June 12, 2020 - Could artificial intelligence help predict which COVID-19 patients will become gravely ill? Could a home-based spit test diagnose COVID-19? Could virtual care after surgery reduce patient returns to hospital?
	Stopping COVID-19 with behavioral science and artificial intelligence June 8, 2020 - Dr. Justin Presseau and colleagues plan to use state-of-the-art behavioural science and artificial intelligence to develop an app that can help people reduce how much they touch their eyes, nose and mouth.
	Mysteries of cell fate unlocked with new measurement and modeling techniques May 14, 2020 - Drs. Marjorie Brand, Ted Perkins and Jeffrey Ranish have found a missing link needed to fully understand how stem cells become specialized cells.
	New COVID-19 projections show how physical distancing can make a huge difference in Ottawa April 8, 2020 - Researchers from The Ottawa Hospital and the University of Ottawa, in partnership with Ottawa Public Health, have created a new interactive Ottawa COVID-19 website, that predicts various scenarios around the number of hospitalizations and deaths in O
	Ottawa doctor recognized as one of the top blood vessel researchers in Canada January 23, 2020 - Dr. Philip Wells has received a major honour recognizing his outstanding contributions to advancing care in blood and blood vessel sciences both in Canada and around the world.
	Could artificial intelligence help manage preterm birth? Prestigious fellowship to help Dr. Steven Hawken find out January 15, 2020 - Dr. Steven Hawken has been awarded a Health Research Foundation Fellowship in Artificial Intelligence (AI) Health Research, one of only two in the country. The $100,000 award will allow Dr. Hawken to use advanced AI and predictive modeling to help id
	The Ottawa Hospital awarded 13 grants worth $11.2 million from Canadian Institutes of Health Research July 26, 2019 - Researchers at The Ottawa Hospital have been awarded 13 grants worth a total of $11.2 million from the Canadian Institutes of Health Research (CIHR). The new projects focus on areas such as cancer immunotherapy, hepatitis C infection, blood clots, ar
	Big data breakthrough: award-winning research helps scientists understand cancer gene expression June 14, 2017 - The Cancer Genome Atlas has generated a whopping 2.5 petabytes (2.5x1012 bytes) of data, giving scientists an extremely powerful tool to understand cancer and develop new treatments. One of the biggest challenges now is to figure out more reliable

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Aviv, Richard MBChB, FRCR (UK), FRCPC, dABR	Clinician Investigator (NS)	Brain and neuromuscular disease, Brain cancer, Head and neck cancer, Multiple sclerosis, Stroke, Subarachnoid hemorrhage, Traumatic brain injury, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Clinical research, Cluster randomized trials, Disease models, Health economics, Health technology, Imaging, Patient safety, Quality Improvement, Translational research
Berardi, Philip MD, PhD, FRCPC	Clinician Investigator (CR)	Aging, Anemia, Bleeding disorders, Blood cancer, Cancer, COVID-19, Health equity, Health in older peoples, Sickle cell anemia, Thalassemia, Thrombosis / thromboembolism	Artificial intelligence and data science, Basic research, Bioinformatics, Biomarkers, Cancer biotherapeutics, Cell therapy, Epigenetics, Gene expression, Genetics, Genomics, Immunotherapy, Molecular and cellular biology, Stem cells, Translational research
Bose, Gauruv MD, FRCPC	Associate Scientist (NS)	Autoimmune diseases of the nervous system, Multiple sclerosis	Artificial intelligence and data science, Biomarkers, Clinical decision rules, Clinical trials, Cohort studies, Health economics
Brand, Marjorie PhD	Senior Scientist Affiliate (RM)	Blood cancer, Sickle cell anemia, Thalassemia, Vascular, heart and metabolic disease	Artificial intelligence and data science, Basic research, Bioinformatics, Disease models, Epigenetics, Gene expression, Genomics, Imaging, Model organisms, Molecular and cellular biology, Proteomics, Stem cells, Systems biology, Transgenic/knockout models
Cook, David PhD	Scientist (CR)	Cancer, Ovarian cancer	Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Drug development, Epigenetics, Gene expression, Genomics, Imaging, Immunotherapy, Molecular and cellular biology, RNA sequencing, Systems biology, Translational research
Dholakia, Saumil MD	Clinician Investigator (NS)	Dementia, Mental health	Artificial intelligence and data science
Diallo, Jean-Simon PhD	Senior Scientist (CR)	Cancer, COVID-19, Infectious disease	Artificial intelligence and data science, Basic research, Cancer biotherapeutics, Cancer immunotherapy, Drug development, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Gilbert, Sebastien MD FRCSC	Clinician Investigator (ACR)	Cancer, Gastric cancer, Gastrointestinal disease, Gastrointestinal stromal tumours (GIST), Lung cancer, Lung disease	Artificial intelligence and data science, Clinical research, Epidemiology, Health technology, Quality Improvement
Hawken, Steven PhD	Senior Scientist (MIR)	Population health, Global health, Newborn and child health, Pregnancy	Artificial intelligence and data science, Big data, Biomarkers, Health services research, Immunization, Biostatistics, Epidemiology, Health research methods
Klein, Ran PhD	Clinician Investigator (MIR)	Cancer, Heart disease, Vascular, heart and metabolic disease	Artificial intelligence and data science, Basic research, Biomarkers, Clinical decision rules, Health technology, Imaging
Mansour, Ramy MSc FRCR	Clinician Investigator (CR)	Arthritis, Bone and joint degeneration, Bone and joint injuries, Musculoskeletal conditions	Artificial intelligence and data science, MRI muscle imaging
Manuel, Douglas MD, MSc, FRCPC	Senior Scientist (MIR)	Aging, Alzheimer's, Cancer, COVID-19, Dementia, Diabetes, Frailty, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, Immigrant and refugee health, Infectious disease, Obesity, Parkinson's, Population health, Stroke, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Big data, Bioinformatics, Biostatistics, Digital and mobile health, Epidemiology, Health research methods, Health services research, Prevention, Public health
McIsaac, Daniel MD, MPH, FRCPC	Scientist (ACR)	Aging, Frailty, Health in older peoples, Pain, Population health	Anesthesiology, Artificial intelligence and data science, Big data, Biostatistics, Clinical research, Clinical trials, Cohort studies, Digital and mobile health, Epidemiology, Health services research, Patient engagement, Peri-operative medicine, Public health, Quality Improvement, Risk assessment, Surgery, Systematic reviews
Nair, Vimoj MBBS MD MSc FRCPC	Clinician Investigator (CR)	Blood cancer, Brain cancer, Colorectal cancer, Gastric cancer, Liver cancer, Pancreatic cancer	Artificial intelligence and data science, Biostatistics, Cancer biotherapeutics, Clinical research, Clinical trials, Health technology, Imaging, Pragmatic trials, Quality Improvement, Translational research
Perkins, Theodore PhD	Senior Scientist (RM)	Brain and neuromuscular disease, Cancer, Muscular dystrophy, Musculoskeletal conditions, Neuromuscular disease	Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Biostatistics, Epigenetics, Gene expression, Genetics, Genomics, Proteomics, Regenerative medicine, Stem cells, Systems biology, Translational research
Presseau, Justin PhD	Senior Scientist (MIR)	Chronic pain, COVID-19, Diabetes, Health equity, Hepatitis C, Immigrant and refugee health, Inflammatory bowel syndrome, Retinal disease, Vision	Artificial intelligence and data science, Health services research, Patient engagement, Psychometrics, Public health, Qualitative methods, Quality Improvement, Rapid reviews, Transfusions, Transplantation, Behaviour, Psychology, Health professional behaviour change, Knowledge translation and implementation research, Health promotion, Cluster randomized trials, Surveys
Rahgozar, Arya PhD	Scientist (MIR)	Aging, Alzheimer's, Brain and neuromuscular disease, Dementia, Parkinson's	Artificial intelligence and data science, Digital and mobile health
Ramsay, Timothy PhD	Senior Scientist (MIR)	Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury	Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Sachs, Adam MD, MA, FRCSC	Associate Scientist (NS)	Amyotrophic lateral sclerosis, Spinal cord injury, Parkinson's	Artificial intelligence and data science, Clinical trials, Imaging, Neuro-stimulation, Surgery
Santos, Marlise MD (FRCPC), MSc, MPH	Clinician Investigator (NS)	Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Seely, Andrew MD/PhD	Scientist (ACR)	COVID-19	Artificial intelligence and data science, Critical care
Stanford, William PhD	Senior Scientist (RM)	Aging, Blood cancer, Cancer, COVID-19, Lung cancer, Lymphangioleiomyomatosis (LAM), Vascular, heart and metabolic disease	Artificial intelligence and data science, Molecular and cellular biology, Regenerative medicine, Stem cells, Systems biology
Thiruganasambandamoorthy, Venkatesh MBBS, CCFP-EM, MSc	Senior Scientist (ACR)	Cardiac arrest, COVID-19, Heart disease, Vascular, heart and metabolic disease	Artificial intelligence and data science, Clinical decision rules, Clinical research, Emergency medicine, Epidemiology, Health services research
Thornhill, Rebecca PhD	Clinician Investigator (MIR)	Cancer, Heart disease, Stroke, Vascular, heart and metabolic disease	Artificial intelligence and data science, Biomarkers, Biostatistics, Imaging, Patient safety
Tsang, Benjamin PhD	Senior Scientist Emeritus (ICD)	Infertility, Ovarian cancer	Artificial intelligence and data science, Basic research, Extracellular vesicles / exosomes, Translational research
Warman Chardon, Jodi MD, PhD FRCPC (Neurology)	Associate Scientist (NS)	Amyotrophic lateral sclerosis, Genetic myopathy, Muscular dystrophy, Neuromuscular disease, Spinal muscular atrophy, Stiff person syndrome	Artificial intelligence and data science, Clinical research, Clinical trials, Exome sequencing analysis, Genetics, Imaging, MRI muscle imaging, Next generation sequencing, RNA sequencing, Genetics
Wells, Philip MD, FRCPC, MSc	Senior Scientist (ICD)	Thrombosis / thromboembolism	Artificial intelligence and data science, Clinical research
Wilson, Kumanan MD, MSc, FRCPC	Senior Scientist (MIR)	COVID-19, Global health, Infectious disease, Newborn and child health, Population health	Artificial intelligence and data science, Big data, Biomarkers, Clinical research, Digital and mobile health, Epidemiology, Health services research, Health technology, Immunization, Public health, Transfusions, Translational research

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