Ottawa Hospital Research Institute

Research News

	Powering up the body’s EVs November 9, 2023 - Dr. Alvin Tieu is receiving the Worton Researcher in Training Award from The Ottawa Hospital for his multidisciplinary research on life-threatening lung diseases
	Beyond the spike: novel COVID vaccine candidate targets 7 viral proteins for strong immune response November 2, 2023 - Despite the widespread availability of COVID-19 vaccines in many countries, SARS-CoV-2 continues to spread and make people sick and new variants remain a significant threat. Researchers at The Ottawa Hospital and the University of Ottawa believe the
	Obstructive sleep apnea linked with severe COVID-19 May 19, 2023 - A study led by Dr. Tetyana Kendzerska suggests that people with obstructive sleep apnea (OSA) could be at greater risk of contracting COVID-19 and having severe complications.
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	Novel stem cell drives ‘remarkable’ regeneration of tiny blood vessels in the lung May 15, 2023 - Dr. Duncan Stewart’s team has identified a novel stem cell with a remarkable ability to regenerate and repair the tiny blood vessels in the lungs.
	COVID-19 vaccines may help reduce inappropriate use of antibiotics May 3, 2023 - Antibiotics were commonly prescribed to older outpatients with COVID-19 in Ontario during the first two years of the pandemic, even though antibiotics do not work against the virus.
	The Ottawa Hospital, the University of Ottawa, and McMaster University join forces to prepare Canada for future pandemics March 2, 2023 - Building on the knowledge gained over nearly three years of the COVID-19 pandemic, The Ottawa Hospital (TOH), the University of Ottawa and McMaster University are joining forces with partners to create the Canadian Pandemic Preparedness Hub (CP2H).
	“Every day is a struggle for me”: A new study is evaluating the effectiveness of a digital app in treating people suffering from long COVID February 28, 2023 - Researchers at The Ottawa Hospital and the Ottawa Hospital Research Institute are studying the effectiveness of a digital health platform in helping people recover from post COVID-19 condition, or long COVID.
	Fireflies help researcher shine a light on COVID-19 November 2, 2022 - As a child watching fireflies in northern Iran, Dr. Taha Azad never dreamed he would someday use the secret behind their glow to help fight cancer and a global pandemic.
	New biomarker could help predict severity of COVID-19 infection October 28, 2022 - New research led by Dr. Benjamin Tsang and Taggart-Parkes postdoctoral fellow Dr. Meshach Asare-Werehene shows that a blood protein called plasma gelsolin (pGSN) could help predict which hospitalized COVID-19 patients are likely to become severely il
	Ottawa-area residents invited to participate in multivalent COVID-19 vaccine trial October 5, 2022 - Healthy adults are invited to participate in a clinical trial at The Ottawa Hospital to test a multivalent coronavirus vaccine candidate developed by VBI Vaccines Inc., a biotechnology company with Ottawa-based research and development facilities.
	Three COVID-19 vaccine doses significantly reduced infection, severe outcomes in organ transplant recipients September 14, 2022 - Dr. Greg Knoll led one of the few real-world studies of the effectiveness of a third dose of COVID-19 vaccine among organ transplant recipients by using linked healthcare databases.
	Anti-fungal drug shows promise against COVID-19 in lab studies August 18, 2022 - Researchers at The Ottawa Hospital have discovered that a common anti-fungal drug can protect against COVID-19 in laboratory models. The drug, called bifonazole, blocks the interaction between the viral spike protein and its cell-surface receptor (AC
	Ottawa researchers contribute to three important studies shaping COVID-19 care April 28, 2022 - Researchers from The Ottawa Hospital continue to play a key role in influential COVID-19 research, with three studies recently published in top-tier journals.
	Researchers at The Ottawa Hospital awarded five grants for high risk, high reward and interdisciplinary research April 4, 2022 - The New Frontiers in Research Fund (NFRF) 2021 Exploration competition has awarded $25 million to support 102 research teams across Canada that bring diverse disciplines together in pursuit of breakthrough ideas and high-reward outcomes.
	New CIHR grants to support an equitable pandemic recovery March 16, 2022 - Researchers at The Ottawa Hospital have been awarded four grants as part of CIHR’s Emerging COVID-19 Research Gaps and Priorities competition, which was designed to support an equitable pandemic recovery for all Canadians.
	Canadian researchers awarded international prize for COVID-19 Evidence Network March 3, 2022 - Dr. Jeremy Grimshaw and Dr. John Lavis recently accepted the international REWARD prize from Cochrane on behalf of the COVID-19 Evidence Network (COVID-END) for their efforts to get reliable and timely COVID-19 evidence summaries to decision makers,
	Scientists call for "living evidence reviews" to combat COVID confusion December 15, 2021 - Policy missteps will continue to overshadow the global response to Covid because policymakers are overwhelmed with rapidly shifting research evidence, according to scientists writing in the peer-reviewed journal Nature.
	Made-in-Ottawa vaccine could help in global fight against COVID-19, including new variants December 13, 2021 - As the COVID-19 virus continues to spread around the world, a vaccine developed and manufactured at The Ottawa Hospital could provide a unique approach to help control the pandemic. Unlike the COVID-19 vaccines currently approved by the World Health
	Medicine’s future: living drugs November 19, 2021 - The Ottawa Hospital’s Biotherapeutics Manufacturing Centre harnessing the life-saving power of biological therapies
	COVID-19 booster shot study recruits Ottawa-area volunteers September 29, 2021 - Ottawa-area adults who are fully vaccinated with a COVID-19 mRNA vaccine are invited to participate in a clinical trial of a locally developed COVID-19 vaccine candidate, as a third dose or late booster vaccine. To be eligible, participants must have
	Major study finds convalescent plasma doesn’t help seriously ill COVID-19 patients September 29, 2021 - A randomized controlled trial involving more than 900 patients has found that convalescent plasma does not reduce the risk of intubation or death for COVID-19 patients.
	Translational Research Grant could spark new approaches to diagnose, treat long COVID September 15, 2021 - Recent studies suggest that more than half of people with COVID-19 will continue to experience symptoms several weeks after infection.
	Biomanufacturing partnership boosts Canada’s life-saving treatment and vaccine capacity September 13, 2021 - As Canada seeks to rebuild its biomanufacturing sector and support made-in-Canada solutions to global health challenges, The Ottawa Hospital, the University of Alberta and BioCanRx have collaborated to create Canada’s first full-service, end-to-end b
	Full-dose blood thinners help moderately ill COVID-19 patients August 23, 2021 - Two Canadian-led studies published in the New England Journal of Medicine show that full-dose blood thinners help moderately ill hospitalized COVID-19 patients, but not critically ill patients.
	Plasma exchange may help treat rare blood clots related to vaccines August 6, 2021 - Canadian researchers have published the first study of plasma exchange as a possible treatment for rare blood clots related to certain COVID-19 vaccines.
	Is there a link between suicide and epidemics? August 1, 2021 - A systematic review published by Dr. Simon Hatcher, in partnership with researchers across Ontario, the United Kingdom, and Ireland, looked at the relationship between public health epidemics and the risk of suicide and self-harm.
	How well do COVID-19 vaccines work in people with cancer, immune conditions and other populations of interest? July 15, 2021 - Researchers at The Ottawa Hospital and the University of Ottawa have been awarded more than $8 million to lead four national studies that will answer important questions about COVID-19 vaccines, including how well they work in people with cancer and
	How long does COVID-19 immunity last and how can we enhance protection for everyone? July 15, 2021 - What is a protective immune response to natural SARS-CoV-2 infection? Does it differ from that induced by vaccination? How many vaccine doses are needed? How long does immunity last? Can natural or vaccine immunity protect against infection by viral
	Biotherapeutics: the future of medicine May 25, 2021 - World-class biotherapeutics facility at The Ottawa Hospital uses cells, genes and viruses to create unique life-saving treatments
	New Canada-Wide Research to Study Mixing-and-Matching COVID-19 vaccines May 20, 2021 - The Government of Canada, through the COVID-19 Immunity Task Force (CITF) and the Vaccine Surveillance Reference Group (VSRG), is supporting a new nation-wide study that will look at the effects of ‘mixing-and-matching’ approved COVID-19 vaccines in
	Ottawa researchers lead $9-million COVID Variant Rapid-Response Network April 28, 2021 - Researchers at The Ottawa Hospital are playing an important role in a University of Ottawa-led project which has been awarded $9 million by the Canadian Institutes of Health Research to create a national network for better researching and responding
	Grateful COVID-19 patient gives back by participating in research April 13, 2021 - Sharon Charlebois doesn’t remember much about the 25 days she spent at The Ottawa Hospital fighting a severe case of COVID-19 in January 2021. Now that she’s recovering at home with her husband, some memories come back to her in flashes.
	Giving every COVID-19 patient the chance to participate in research March 17, 2021 - Most patients admitted to The Ottawa Hospital with COVID-19 have probably met Irene Watpool or Rebecca Porteous, even if they don’t remember it. Since the beginning of the pandemic, Irene and Rebecca have been on the front lines explaining all the av
	Research study to improve patient care during pandemic March 17, 2021 - Meagan Gordon spent much of her high-risk twin pregnancy confined to a room at our hospital to keep her and her babies safe during the COVID-19 pandemic. Now, she's helping our researchers improve care.
	Ottawa-area residents invited to participate in COVID-19 vaccine trial March 9, 2021 - Healthy adults are invited to participate in a clinical trial at The Ottawa Hospital to test a COVID-19 vaccine candidate developed by VBI Vaccines Inc., a biotechnology company with Ottawa-based research and development facilities.
	The Ottawa Hospital manufactures COVID-19 vaccines for clinical trials February 25, 2021 - The Ottawa Hospital’s Biotherapeutics Manufacturing Centre (BMC) is manufacturing three COVID-19 vaccines for human clinical trials, filling a critical gap in Canada’s vaccine manufacturing capacity.
	Blood thinners help keep hospitalized COVID-19 patients out of ICU February 17, 2021 - Full-dose blood thinners reduced the need for mechanical ventilation and transfer to the ICU in moderately ill patients hospitalized with COVID-19, according to interim results from an international clinical trial.
	Fewer domestic violence and sexual assault survivors presented for care in Ottawa EDs during the 2020 spring lockdown February 4, 2021 - The Ottawa Hospital saw a decrease in emergency department admissions for sexual assault and domestic violence in the early days of COVID-19, according to a study published in BMC Medicine.
	Experimental stem cell therapy a potential weapon against COVID-19 February 1, 2021 - Drs. Duncan Stewart, Shane English, Dean Fergusson and colleagues have launched a clinical trial to test MSCs in people with severe COVID-19.
	Government of Canada invests $1M in a COVID-19 evidence network to support decision-making January 12, 2021 - To ensure decision-makers have access to the best COVID-19 science in a timely manner, the Government of Canada is investing $1M in the COVID-19 Evidence Network to support Decision-making (COVID-END)
	Understanding the impact of COVID-19 on women December 30, 2020 - Dr. Innie Chen is leading research to understand the impact of COVID-19 on women, thanks to seed funding through The Ottawa Hospital Foundation’s COVID-19 Emergency Response Fund.
	COVID-19 and rheumatoid arthritis: using big data to understand risks and improve treatments December 10, 2020 - Rheumatoid arthritis is an inflammatory disease that primarily affects the joints. Dr. Sibel Aydin is harnessing big data from ICES and the Ontario Best Practice Research Initiative to determine if people with rheumatoid arthritis are more or less li
	Can chest imaging diagnose COVID-19? December 9, 2020 - An international team led by Dr. Matthew McInnes is regularly combing the latest research to find out whether chest imaging could be a useful tool for diagnosing COVID-19.
	World-first clinical trial aims to protect cancer patients from COVID-19 December 9, 2020 - Our researchers are leading the way in a world-first clinical trial to protect vulnerable cancer patients during the COVID-19 pandemic.
	Vaccines and viral immunotherapies: unique Canadian program provides training to manufacture biotherapeutics November 21, 2020 - As COVID-19 highlights the urgent need to increase vaccine manufacturing around the world, a unique training program is bolstering Canada’s capacity to manufacture vaccines, as well as viral immunotherapies for cancer and other emerging biotherapeuti
	App could provide new way to track vaccine safety November 17, 2020 - Vaccines are one of society’s greatest success stories, but like any treatment, there can be rare adverse events and they must be tested carefully. With a massive COVID-19 vaccination campaign on the horizon, Canadian researchers have launched a pilo
	$1M grant to support manufacturing of COVID-19 treatments and vaccines at The Ottawa Hospital and uOttawa November 6, 2020 - Researchers from The Ottawa Hospital and the University of Ottawa have been awarded $1,050,000 from the Canada Foundation for Innovation to support facilities for manufacturing innovative treatments and vaccines for COVID-19.
	Probing the mysteries of COVID immunity October 15, 2020 - Stop the Spread Ottawa is an initiative aimed at accelerating vaccine development against the novel coronavirus that has transformed our way of life.
	The Ottawa Hospital and uOttawa launch new cancer immunotherapy research projects with funding from BioCanRx September 22, 2020 - BioCanRx, Canada’s Immunotherapy Network, today announced funding of $10M for 14 cancer immunotherapy research projects and eight core and biomanufacturing facilities across the country. Researchers at The Ottawa Hospital (TOH) and the University of
	How to mitigate ICU drug shortages related to COVID-19 September 9, 2020 - As COVID-19 continues to disrupt global drug supplies, researchers at The Ottawa Hospital are playing a key role in developing and implementing mitigation strategies for intensive care units (ICUs).
	Canadian study compares COVID-19 spit test to traditional swab test September 8, 2020 - A new study led by researchers at The Ottawa Hospital, University of Ottawa and the Public Health Agency of Canada’s National Microbiology Laboratory shows that a Canadian-made spit test can detect the COVID-19 virus.
	Protecting cancer patients from COVID-19 July 8, 2020 - In the race to find new ways to prevent and treat COVID-19, Canadian researchers have launched an innovative clinical trial focussed on strengthening the immune system for one of the most vulnerable populations – cancer patients.
	Hyperbaric oxygen therapy for COVID pneumonia June 26, 2020 - Astudy led by Dr. Sylvain Boet will test if hyperbaric oxygen therapy may be able to help some people with COVID-19 pneumonia.
	Preventing dangerous blood clots in COVID-19 patients June 26, 2020 - Drs. Lana Castellucci, Marc Carrier and colleagues are contributing to an international clinical trial to find out whether a high dose of blood thinner can prevent dangerous blood clots in hospitalized COVID-19 patients.
	Using big data to find promising drugs for COVID-19 June 26, 2020 - Dr. Derek MacFadden and his colleagues plan to identify promising drugs to treat COVID-19 by analyzing past data from 3,000 Ontario patients treated for other kinds of coronavirus infections.
	Understanding the impact of COVID-19 on pregnant women and babies June 25, 2020 - Very little is known about how COVID-19 affects pregnant women and their babies. Drs. Darine El-Chaâr, Marc-André Langlois and their team plan to address this knowledge gap through several large studies. Dr Langlois’s team will be responsib
	Harnessing cancer-fighting viruses to develop a COVID-19 vaccine June 25, 2020 - Drs. Carolina Ilkow, John Bell and colleagues are harnessing their expertise in making oncolytic (cancer-fighting) viruses to develop a vaccine against COVID-19, in partnership with scientists and clinicians in Canada and around the world.
	The Ottawa Hospital awarded $4.7 million for COVID-19 research from the Canadian Institutes of Health Research June 25, 2020 - Researchers at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $4.7 million from the Canadian Institutes of Health Research (CIHR) for four research projects that could transform our understanding of COVID-19 and lead
	Helping COVID-19 survivors stay healthy June 23, 2020 - Drs. Sara J. Abdallah and Juthaporn Cowan will study the long-term effects of COVID-19 in survivors, checking in on them three, six and 12 months after they were initially infected.
	TOHAMO awards $1.2M for COVID-19 research projects June 12, 2020 - Could artificial intelligence help predict which COVID-19 patients will become gravely ill? Could a home-based spit test diagnose COVID-19? Could virtual care after surgery reduce patient returns to hospital?
	Can virtual care after surgery reduce patient returns to hospital? Research study now open in Ottawa June 10, 2020 - COVID-19 has accelerated the adoption of all kinds of virtual health care, from phone and video appointments to tools that monitor symptoms remotely. The Ottawa Hospital continues to be at the forefront of this trend with the launch of an innovative
	Using lab-grown human tissues to identify possible treatments June 8, 2020 - Dr. William Stanford and his colleagues are using human tissue models to understand why COVID-19 makes some patients severely ill.
	Stopping COVID-19 with behavioral science and artificial intelligence June 8, 2020 - Dr. Justin Presseau and colleagues plan to use state-of-the-art behavioural science and artificial intelligence to develop an app that can help people reduce how much they touch their eyes, nose and mouth.
	Understanding the challenge of COVID-19 for Ottawa’s most vulnerable people June 8, 2020 - Dr. Smita Pakhale and her colleagues will harness the trust and engagement they have built with Ottawa’s most marginalized communities over the last 10 years through community-based participatory action research to examine how COVID-19 has impacted t
	Mobile reporting of adverse events from a pandemic COVID-19 vaccine June 8, 2020 - Dr. Kumanan Wilson and his colleagues will harness their electronic vaccine-tracking platform CANImmunize to let Canadians report potential adverse events from a COVID-19 vaccine through their mobile device.
	Could blood plasma shore up our COVID defenses? June 5, 2020 - A team led by Dr. Alan Tinmouth and Dr. Dean Fergusson is part of a collaboration aiming to settle the long-standing question of whether “convalescent” blood plasma from recovered patients can be used to treat actively sick ones.
	Creating a new mouse model to study COVID-19 lung disease June 4, 2020 - Researchers are working to develop a mouse model of COVID-19 that mimics the severe lung disease seen in humans. The lack of good, accessible animal models of this disease is severely limiting research around the world.
	Studying the immune response of COVID-19 patients in the ICU June 4, 2020 - A study led by Dr. Shirley Mei will examine why some people get severely ill and die of COVID-19, while others experience only mild symptoms
	Experimental Stem Cell Therapy a Potential Weapon in COVID-19 Fight May 28, 2020 - Ottawa-based researchers pivot at lightning speed to launch study on treating related respiratory failure
	COVID-19 research on cell therapy, drug screening and marginalized populations funded through Ontario’s Rapid Research Fund May 21, 2020 - Researchers from The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded almost $2 million from Ontario’s COVID-19 Rapid Research Fund for three research projects that could help in the fight against the virus. These three pr
	Thanking the heroes behind clinical trials May 20, 2020 - COVID-19 has put a special focus on the importance of clinical trials in finding ways to diagnose, treat and prevent this new infection, but clinical trials have always been essential to improving care and saving lives at The Ottawa Hospital. Six cli
	COVID-19 Evidence Network to support decision-making May 11, 2020 - To help leaders around the world respond to unprecedented challenges related to COVID-19, Drs. Jeremy Grimshaw and John Lavis are co-leading The COVID-19 Evidence Network to support Decision-making (COVID-END). Partners in the network include experts
	COVID-19 research moving at ‘lightning speed’, thanks to generous community support May 8, 2020 - Researchers at The Ottawa Hospital are working around the clock to advance more than 50 potentially life-saving research projects to support the world-wide effort to find better ways to treat and prevent COVID-19. Now, nine of these projects have bee
	Researchers use lab-grown human tissues to understand secrets of COVID-19 infection, identify possible treatments April 29, 2020 - A team of Ontario researchers is using 3D lab-grown human tissue models to understand why COVID-19 makes some patients severely ill. They also hope to identify drugs that can reduce the severity of the infection.
	Cancer-killing viruses provide inspiration for COVID-19 vaccine April 28, 2020 - While physical distancing has slowed the spread of COVID-19, the vast majority of people around the world remain susceptible to the virus. That’s why most experts believe we won’t be able to fully find a new normal until a vaccine is developed. At T
	Clinical trial to test plasma from recovered COVID-19 patients as possible treatment April 28, 2020 - Researchers, clinicians and patients at The Ottawa Hospital will be contributing to the global effort to determine if plasma from people who have recovered from COVID-19 (called convalescent plasma) could be an effective treatment for actively infect
	Harnessing stem cells and regenerative medicine to fight COVID-19 April 23, 2020 - Researchers from The Ottawa Hospital and the University of Ottawa have been awarded $490,000 from the Stem Cell Network for two research projects that could help in the fight against COVID-19. These peer-reviewed grants are part of an overall investm
	Should I leave my retirement or long-term care home due to COVID-19? New tools can help with tough decisions April 22, 2020 - Researchers from The Ottawa Hospital, the University of Ottawa, the Champlain Local Health Integration Network?and the National Institute of Ageing have developed tools to help seniors decide if they should temporarily move out of their retirement, a
	How are you coping during COVID-19? April 20, 2020 - COVID-19 is changing core aspects of people’s lives in a unique manner. Social interactions, family and work are all affected. Researchers want to understand the impacts of these changes and determine what helps people cope.? They have launched a stu
	Don’t change blood pressure medication because of fear of COVID-19 April 17, 2020 - Viruses get inside our cells by latching onto specific proteins on the cell surface. In the case of COVID-19, the virus latches onto a protein that normally controls blood pressure. In fact, common blood pressure medications increase the level of thi
	New COVID-19 projections show how physical distancing can make a huge difference in Ottawa April 8, 2020 - Researchers from The Ottawa Hospital and the University of Ottawa, in partnership with Ottawa Public Health, have created a new interactive Ottawa COVID-19 website, that predicts various scenarios around the number of hospitalizations and deaths in O
	Researchers join the fight against COVID-19 April 2, 2020 - As hospitals and communities band together to fight COVID-19, researchers at The Ottawa Hospital are harnessing their unique expertise and resources to help.
	A COVID-19 palliative care pandemic plan: An essential tool March 31, 2020 - Palliative care physicians have created a coronavirus disease 2019 (COVID-19) palliative care plan as an essential tool to provide care and help manage scare resources during the pandemic. The plan, which focuses on 8 critical elements -- "stuff

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Aydin, Sibel MD	Associate Scientist (ICD)	Arthritis, Autoimmune disease, Bone and joint degeneration, COVID-19, Population health	Epidemiology, Imaging
Bell, John PhD, FRSC, FCAHS	Senior Scientist (CR)	Cancer, COVID-19	Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Immunization, Immunotherapy, Oncolytic viruses, Translational research, Viral therapy
Berardi, Philip MD, PhD, FRCPC	Clinician Investigator (CR)	Aging, Anemia, Bleeding disorders, Blood cancer, Cancer, COVID-19, Health equity, Health in older peoples, Sickle cell anemia, Thalassemia, Thrombosis / thromboembolism	Artificial intelligence and data science, Basic research, Bioinformatics, Biomarkers, Cancer biotherapeutics, Cell therapy, Epigenetics, Gene expression, Genetics, Genomics, Immunotherapy, Molecular and cellular biology, Stem cells, Translational research
Bissell, Mary Beth MSc, MD, FRCPC	Clinician Investigator (CR)	Breast cancer, Cancer, COVID-19, Population health, Women's health	Clinical research
Boet, Sylvain MD, PhD	Scientist (ACR)	COVID-19	Anesthesiology, Behaviour, Clinical trials, Knowledge translation and implementation research, Patient engagement, Psychology, Qualitative methods, Quality Improvement, Surgery, Systematic reviews, Translational research
Cameron, Bill MD FRCPC FACP FIDSA	Senior Scientist (ICD)	Chronic obstructive pulmonary disease, COVID-19, Cystic fibrosis, HIV, Infectious disease, Sexually transmitted infections, Tuberculosis	Clinical research, Epidemiology, Immunization, Immunotherapy, Pharmacology
Cooper, Curtis MD, FRCPC	Scientist (ICD)	COVID-19, Hepatitis C, HIV, Infectious disease, Influenza	Clinical research, Immunization
Cowan, Juthaporn MD, PhD, FRCPC	Associate Scientist (ICD)	Autoimmune disease, COVID-19, Infectious disease	Immunization, Immunotherapy, Patient engagement
Crawley, Angela Ph.D.	Senior Scientist (ICD)	Cancer, COVID-19, Hepatitis C, HIV, Infectious disease, Liver cancer, Liver disease	Basic research, Cancer immunotherapy, Clinical research, Disease models, Immunization, Immunotherapy, Molecular and cellular biology, RNA sequencing, Translational research
Diallo, Jean-Simon PhD	Senior Scientist (CR)	Cancer, COVID-19, Infectious disease	Artificial intelligence and data science, Basic research, Cancer biotherapeutics, Cancer immunotherapy, Drug development, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
El-Chaar, Darine MD, FRCSC, Msc	Scientist (ICD)	Autoimmune disease, COVID-19, Diabetes, Infectious disease, Inflammatory bowel syndrome, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health research methods, Health services research, Public health, Qualitative methods, Quality Improvement, Systematic reviews
English, Shane MD	Senior Scientist (ACR)	COVID-19, Septic shock, Subarachnoid hemorrhage, Traumatic brain injury	Clinical research, Critical care, Patient engagement
Fergusson, Dean PhD, MHA, FCAHS	Program Director and Senior Scientist (MIR)	Cancer, COVID-19, Kidney disease, Septic shock, Vascular, heart and metabolic disease	Clinical trials, Health services research, Health technology, Patient engagement, Pragmatic trials, Surveys, Translational research, Biostatistics, Clinical research, Cluster randomized trials, Cohort studies, Critical care, Health research methods, Qualitative methods, Quality Improvement, Systematic reviews, Transfusions
Grimshaw, Jeremy MBCHB, PHD	Senior Scientist Emeritus (MIR)	COVID-19	Behaviour, Cluster randomized trials, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Qualitative methods, Quality Improvement, Surveys, Systematic reviews
Hatcher, Simon BSc MBBS MMedSc MD FRCPC FRANZCP MRCPsych	Scientist (NS)	Anxiety, Brain and neuromuscular disease, COVID-19, First Nations, Inuit and Métis Health, Health equity, Mental health, Traumatic brain injury, Depression, Health in disadvantaged peoples, Suicide	Clinical research, Digital and mobile health, Health economics, Health professional behaviour change, Health research methods, Health services research, Health technology, Knowledge translation and implementation research, Patient engagement, Prevention, Public health, Qualitative methods, Clinical trials, Cluster randomized trials, Epidemiology, Psychology, Systematic reviews
Ilkow, Carolina PhD	Senior Scientist (CR)	Breast cancer, COVID-19, Ovarian cancer, Pancreatic cancer	Basic research, Cancer biotherapeutics, Cancer immunotherapy, Extracellular vesicles / exosomes, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Lalu, Manoj MD, PhD, FRCPC	Scientist (ACR)	Blood cancer, COVID-19, Heart disease, Stroke, Vascular, heart and metabolic disease	Anesthesiology, Basic research, Cell therapy, Clinical research, Clinical trials, Disease models, Health research methods, Model organisms, Patient engagement, Regenerative medicine, Stem cells, Translational research
Manuel, Douglas MD, MSc, FRCPC	Senior Scientist (MIR)	Aging, Alzheimer's, Cancer, COVID-19, Dementia, Diabetes, Frailty, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, Immigrant and refugee health, Infectious disease, Obesity, Parkinson's, Population health, Stroke, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Big data, Bioinformatics, Biostatistics, Digital and mobile health, Epidemiology, Health research methods, Health services research, Prevention, Public health
Mei, Shirley PhD, MSc	Investigator (RM)	COVID-19, Septic shock	Basic research, Biomarkers, Cell therapy, Critical care, Disease models, Epigenetics, Gene therapy, Knowledge translation and implementation research, Molecular and cellular biology, Regenerative medicine, Stem cells
Pakhale, Smita MD, FRCPC, MSc (Epi & Biostat)	Senior Scientist (ICD)	COVID-19, First Nations, Inuit and Métis Health, Health equity, Health in disadvantaged peoples, Lung disease, Sickle cell anemia	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health economics, Health promotion, Health services research, Patient engagement, Pragmatic trials, Public health, Quality Improvement
Presseau, Justin PhD	Senior Scientist (MIR)	Chronic pain, COVID-19, Diabetes, Health equity, Hepatitis C, Immigrant and refugee health, Inflammatory bowel syndrome, Retinal disease, Vision	Artificial intelligence and data science, Health services research, Patient engagement, Psychometrics, Public health, Qualitative methods, Quality Improvement, Rapid reviews, Transfusions, Transplantation, Behaviour, Psychology, Health professional behaviour change, Knowledge translation and implementation research, Health promotion, Cluster randomized trials, Surveys
Seely, Andrew MD/PhD	Scientist (ACR)	COVID-19	Artificial intelligence and data science, Critical care
Stanford, William PhD	Senior Scientist (RM)	Aging, Blood cancer, Cancer, COVID-19, Lung cancer, Lymphangioleiomyomatosis (LAM), Vascular, heart and metabolic disease	Artificial intelligence and data science, Molecular and cellular biology, Regenerative medicine, Stem cells, Systems biology
Stewart, Duncan MD, FRCPC	Senior Scientist (RM)	COVID-19, Heart disease, Pulmonary hypertension, Septic shock, Vascular, heart and metabolic disease	Extracellular vesicles / exosomes, Stem cells, Cell therapy, Clinical trials, Molecular and cellular biology, Regenerative medicine, Translational research
Thavorn, Kednapa BPharm, MPharm, PhD	Senior Scientist (MIR)	Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision	Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews
Thiruganasambandamoorthy, Venkatesh MBBS, CCFP-EM, MSc	Senior Scientist (ACR)	Cardiac arrest, COVID-19, Heart disease, Vascular, heart and metabolic disease	Artificial intelligence and data science, Clinical decision rules, Clinical research, Emergency medicine, Epidemiology, Health services research
Tinmouth, Alan MD, FRCPC, MSc (Clin Epi)	Senior Scientist (ICD)	COVID-19, Sickle cell anemia, Thalassemia	Clinical trials, Epidemiology, Transfusions
Wilson, Kumanan MD, MSc, FRCPC	Senior Scientist (MIR)	COVID-19, Global health, Infectious disease, Newborn and child health, Population health	Artificial intelligence and data science, Big data, Biomarkers, Clinical research, Digital and mobile health, Epidemiology, Health services research, Health technology, Immunization, Public health, Transfusions, Translational research

Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "COVID-19” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

Publications

The following research publications are pulled from PubMed using the search terms "COVID-19" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Accuracy of the Canadian COVID-19 Mortality Score (CCMS) to predict in-hospital mortality among vaccinated and unvaccinated patients infected with Omicron: a cohort study.
2024-11-21

Obesity does not influence SARS-CoV-2 humoral vaccine immunogenicity.
2024-11-19

COVID-19-related research data availability and quality according to the FAIR principles: A meta-research study.
2024-11-18

Beyond Hemoglobin A1c-Outcomes That Matter to Individuals With Type 1 Diabetes in Adopting Digital Health Interventions for Self-Management Support: Qualitative Study.
2024-11-13

Burden of Illness Associated With Respiratory Syncytial Virus, Influenza, and Coronavirus Disease 2019 in Infants and Young Children in Ontario, Canada, 2018-2023: A Population-Based Canadian Immunization Research Network Study.
2024-10-30

Consensus Considerations and Good Practice Points for Use of Continuous Glucose Monitoring Systems in Hospital Settings.
2024-10-25

Impact of the COVID-19 Pandemic on the Canadian Dermatology Residency Match: A Four-Year Retrospective.
2024-10-22

Comparing AI/ML approaches and classical regression for predictive modeling using large population health databases: Applications to COVID-19 case prediction.
2024-10-22

Coronavirus disease 2019 outcomes in a population-based cohort of people with HIV and a matched cohort of people without HIV during Omicron variant waves.
2024-10-18

Post-COVID-19 condition symptoms among emergency department patients tested for SARS-CoV-2 infection.
2024-10-01

View more on PubMed