Gene expression

Research News


Studying sex differences in kidney disease could open door to developing new treatments Studying sex differences in kidney disease could open door to developing new treatments
January 27, 2021 - During critical illnesses like septic shock, the kidneys are often the first to shut down and the last to recover, if they recover at all. Previous research has shown that men are more severely affected by this kind of acute kidney injury than women,
Depression linked to “junk DNA” in the serotonin receptor gene Depression linked to “junk DNA” in the serotonin receptor gene
November 21, 2018 - The human genome is thought to be 75 to 90 percent meaningless “junk DNA”, but researchers are increasingly finding that some of this junk may actually do something important. For example, new research led by Dr. Paul Albert and Dr. Eitan Friedman sh
How does type 1 diabetes start? New research implicates early metabolic defects in the pancreas How does type 1 diabetes start? New research implicates early metabolic defects in the pancreas
September 6, 2018 - Type 1 diabetes (T1D) is often diagnosed in the teenage years, but the disease process probably starts much earlier. New research led by Dr. Fraser Scott shows that cellular stress is linked to decreased insulin and increased glucagon production in t


Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Albert, Paul
PhD
Senior Scientist
(NS) 		Mental health, Vascular cognitive impairment, Anxiety, Depression, Intellectual disabilities, Parkinson's, Schizophrenia, Stroke, Suicide Basic research, Epigenetics, Exercise, Gene expression, Translational research, Disease models, Epigenetics, Genetics, Imaging, Molecular and cellular biology, Optogenetics, Transgenic/knockout models
Berardi, Philip
MD, PhD, FRCPC
Clinician Investigator
(CR) 		Aging, Anemia, Bleeding disorders, Blood cancer, Cancer, COVID-19, Health equity, Health in older peoples, Sickle cell anemia, Thalassemia, Thrombosis / thromboembolism Artificial intelligence and data science, Basic research, Bioinformatics, Biomarkers, Cancer biotherapeutics, Cell therapy, Epigenetics, Gene expression, Genetics, Genomics, Immunotherapy, Molecular and cellular biology, Stem cells, Translational research
Brand, Marjorie
PhD
Senior Scientist Affiliate
(RM) 		Blood cancer, Sickle cell anemia, Thalassemia, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Bioinformatics, Disease models, Epigenetics, Gene expression, Genomics, Imaging, Model organisms, Molecular and cellular biology, Proteomics, Stem cells, Systems biology, Transgenic/knockout models
Burns, Kevin
MD CM, FRCPC
Senior Scientist
(ICD) 		Diabetes, Kidney disease, Vascular, heart and metabolic disease Basic research, Biomarkers, Cell therapy, Clinical research, Disease models, Extracellular vesicles / exosomes, Gene expression, Molecular and cellular biology, Regenerative medicine, Stem cells, Transgenic/knockout models, Translational research
Chen, Hsiao-Huei
PhD
Senior Scientist
(NS) 		Aging, Autism, Dementia, Depression, Heart disease, Maternal and fetal health, Mental health, Tourette's, Alzheimer's, Alzheimer's, Anxiety, Diabetes, Obesity, Schizophrenia, Stroke, Vascular, heart and metabolic disease Disease models, Drug development, Gene expression, Neuro-stimulation, Optogenetics, Transgenic/knockout models, Basic research, Molecular and cellular biology, Translational research
Cook, David
PhD
Scientist
(CR) 		Cancer, Ovarian cancer Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Drug development, Epigenetics, Gene expression, Genomics, Imaging, Immunotherapy, Molecular and cellular biology, RNA sequencing, Systems biology, Translational research
Coutu, Daniel
PhD
Scientist
(RM) 		Aging, Arthritis, Autoimmune disease, Bleeding disorders, Blood cancer, Bone and joint degeneration, Bone and joint injuries, Musculoskeletal conditions, Osteoporosis Basic research, Bioinformatics, Biomaterials, Cell therapy, Gene expression, Gene therapy, Genetics, Genomics, Imaging, Immunotherapy, Molecular and cellular biology, Proteomics, Regenerative medicine, Stem cells, Surgery, Systems biology, Transgenic/knockout models, Translational research
Dilworth, Jeffrey
PhD
Senior Scientist Affiliate
(RM) 		Aging, Muscular dystrophy, Neuromuscular disease Basic research, Epigenetics, Gene expression, Genomics, Molecular and cellular biology, Proteomics, Regenerative medicine, Stem cells
Gage, Blair
PhD
Scientist
(RM) 		Bleeding disorders, Diabetes, Liver cancer, Liver disease, Vascular, heart and metabolic disease Basic research, Bioinformatics, Cell therapy, Disease models, Gene expression, Gene therapy, Genetics, Genomics, Model organisms, Molecular and cellular biology, Regenerative medicine, Stem cells, Translational research, Transplantation
Lacoste, Baptiste
PhD
Senior Scientist
(NS) 		Stroke, Vascular cognitive impairment, Autism Basic research, Disease models, Gene expression, Genomics, Stem cells, Genetics, Imaging, Model organisms, Molecular and cellular biology, Transgenic/knockout models
Mattar, Pierre
PhD
Senior Scientist
(RM) 		Autism, Autoimmune diseases of the nervous system, Glaucoma, Intellectual disabilities, Macular degeneration, Retinal disease, Vision Basic research, Bioinformatics, Cell therapy, Epigenetics, Gene expression, Genetics, Genomics, Model organisms, Molecular and cellular biology, Proteomics, Regenerative medicine, Stem cells, Systems biology, Transgenic/knockout models
Nessim, Carolyn
MD, MSc, FRCSC, FACS
Clinician Investigator
(CR) 		Cancer, Colorectal cancer, Gastric cancer, Gastrointestinal disease, Gastrointestinal stromal tumours (GIST), Soft tissue sarcoma, Skin cancer Biomarkers, Clinical trials, Gene expression, Immunotherapy, Surgery, Translational research, Viral therapy, Clinical research, Immunotherapy
Perkins, Theodore
PhD
Senior Scientist
(RM) 		Brain and neuromuscular disease, Cancer, Muscular dystrophy, Musculoskeletal conditions, Neuromuscular disease Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Biostatistics, Epigenetics, Gene expression, Genetics, Genomics, Proteomics, Regenerative medicine, Stem cells, Systems biology, Translational research
Sabourin, Luc
PhD
Senior Scientist
(CR) 		Breast cancer, Muscular dystrophy, Skin cancer Basic research, Disease models, Drug development, Gene expression, Genetics, Molecular and cellular biology, Proteomics, Stem cells, Transgenic/knockout models
Vanderhyden, Barbara
PhD
Senior Scientist
(CR) 		Cancer, Infertility, Ovarian cancer, Women's health Basic research, Bioinformatics, Biomarkers, Cancer biotherapeutics, Disease models, Drug development, Epigenetics, Gene expression, Genomics, Immunotherapy, Model organisms, Molecular and cellular biology, Oncolytic viruses, Stem cells, Transgenic/knockout models, Translational research, Viral therapy