Researchers at The Ottawa Hospital are playing a lead role in eight new projects awarded $5 million from the Canadian Institutes of Health Research (CIHR).
These projects will advance science and improve health in areas such as cancer immunotherapy, orthopedic surgery, long-term care, neuromuscular disease, blood clots, vascular disease, aging, kidney disease and Inuit health.
“Research projects such as these will help us provide the best care possible for our patients and community, while advancing science and improving health on a global scale,” said Dr. Duncan Stewart, Executive Vice-President of Research at The Ottawa Hospital and professor at the University of Ottawa. “I’m proud that The Ottawa Hospital has consistently ranked as one of the top hospitals in the country for highly-competitive CIHR funding, ranking fourth overall in 2020-21.”
The new grants include:
When the Killers become Thieves: NK cells are suppressed by trogocytosed PD-1
Periacetabular Osteotomy with or without arthroscopic management in patients with hip dysplasia: A multicenter randomized controlled trial
- Principal Investigators: Beaulé, Paul; Grammatopoulos, George; Poitras, Stéphane; Wilkin, Geoffrey P
- Co-Investigators: Ramsay, Timothy O; Thavorn, Kednapa; Zaltz, Ira; Belzile, Etienne L; Melkus, Gerd E; Rakhra, Kawan S; Clohisy, John; Smit, Kevin
- Amount: $669,376
Models for Primary Medical Care, Nursing Care and Personal Care in Long-Term Care Homes: Systematic Reviews to Inform Change in Canada
- Principal Investigators: Hutton, Brian E; Watt, Jennifer A
- Co-Investigators: Garritty, Chantelle M; Wong, Eric K; Straus, Sharon E; Welch, Vivian A; Shea, Beverley J; Lunny, Carole A
- Amount: $110,925
Extracellular vesicles as a biomarker and therapeutic for Spinal Muscular Atrophy
- Principal Investigator: Parks, Robin J
- Co-Investigators: Vacratsis, Panayiotis; Warman Chardon, Jodi; Kothary, Rashmi K
- Amount: $960,076
Regulation of the epigenome by replication stress in vascular disease and aging
- Principal Investigators: Stanford, William L; Hendzel, Michael J
- Co-Investigators: Dilworth, F J; Perkins, Theodore J
- Amount: $1,002,150
Reducing bleeding with DOACs in breast cancer patients: The STOP-Bleed Cancer Study
Filling Knowledge Gaps for the Success of Ontario Renal Plan 3
- Principal Investigators: Weir, Matthew A; Beaucage, Mary B; Blake, Peter G; Chanchlani, Rahul; Clark, Edward G; Clemens, Kristin K; Dixon, Stephanie N; Harel, Ziv; Jain, Arsh K; Molnar, Amber; Silver, Samuel; Sood, Manish M; Zappitelli, Michael
- Co-Investigators: Al-Jaishi, Ahmed; Bathini, Lavanya; Bhasin, Arrti A; Cowan, Andrea; Field, Bonnie; Garg, Amit; Harvey-Rioux, Linda; Jaakkimainen, R. Liisa; Kim, Sang J; Kitchlu, Abhijat; Knoll, Gregory; Kurdyak, Paul A; Muanda, Flory; Nash, Danielle M; Naylor, Kyla; Nesrallah, Gihad; Oliver, Matthew J; Ordon, Michael; Paterson, Michael; Perl, Jeffrey; Roshanov, Pavel; Sontrop, Jessica M; Sultan, Heebah; Vorster, Arris H; Wald, Ron; Walsh, Michael W; Wang, Carol; Welk, Blayne K; Yau, Kevin; Young, Ann
- Amount: $1,143,676
- Note: this grant is administered at London Health Sciences Centre
Aajiiqatigiinniq: A field-test of shared decision making education for healthcare providers who work with Inuit
- Principal Investigators: Jull, Janet E; Dorschner, Danielle; Maniate, Jerry; Tungasuvvingat Inuit, Tungasuvvingat Inuit
- Co-Investigators: Barton, Gwen; Fairman, Kimberly D; Hesmer, Brittany; Kangok, Kim; Zehr, Malaya
- Amount: $665,551
- Note: this grant is administered at Queen’s University
These projects are supported by core research resources at The Ottawa Hospital, such as the Ottawa Methods Centre, the Bioinformatics Facility, the Human Pluripotent Stem Cell Facility and High Content Imaging.
The Ottawa Hospital is a leading academic health, research and learning hospital proudly affiliated with the University of Ottawa and supported by The Ottawa Hospital Foundation.
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613-614-5253
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