Des chercheurs de L’Hôpital d’Ottawa sont à la barre de 13 nouveaux projets qui ont reçu un financement de plus de 7 millions de dollars des Instituts de recherche en santé du Canada (IRSC).

« Les projets de recherche de ce type nous permettent d’offrir d’excellents soins aux patients tout en réalisant des percées scientifiques qui améliorent la santé à l’échelle mondiale », affirme le Dr Duncan Stewart, vice-président exécutif de la Recherche à L’Hôpital d’Ottawa et professeur à l’Université d’Ottawa. 

Les nouvelles subventions comprennent les suivantes :

The Taima TB wastewater study - $3,037,050

• Principal Investigator(s): Alvarez, Gonzalo G; Sun, Jim; Delatolla, Robert; Allen, Jean M
• Co-Investigator(s): Ward, Leonor; Desjardins, Marc; Graber, Tyson; Mallick, Ranjeeta; Aaron, Shawn D; Mulpuru, Sunita; Brophy, Jason C; Pease, Christopher; Cameron, D.William

Overcoming barriers to effective cancer immunotherapy with an engineered virus based therapeutic -$100,000

• Principal Investigator(s): Bell, John C
• Co-Investigator(s): Boulton, Stephen; Crupi, Mathieu J; Ardolino, Michele

Colchicine to Quench the Inflammatory Response after Deep Vein Thrombosis:  A Pilot Randomized Controlled Trial - CONQUER-DVT Pilot Trial - $374,850

• Principal Investigator(s): Carrier, Marc; Siegal, Deborah M; Le Gal, Grégoire; Kahn, Susan R; Shivakumar, Sudeep P
• Co-Investigator(s): Duffett, Lisa; Cervi, Andrea L; Abdulrehman, Jameel; Mai, Vicky; Leonard, Blair J; Mallick, Ranjeeta; Chan, Noel; Lazo-Langner, Alejandro; Munro, Camille; Douketis, James D; Delluc, Aurelien; Potere, Nicola; Ramsay, Timothy O

COBRRA trial: Comparison of Bleeding Risk between Rivaroxaban and Apixaban for the treatment of acute venous thromboembolism - $634,951

• Principal Investigator(s): Castellucci, Lana
• Co-Investigator(s): Kahn, Susan R; Kovacs, Michael J; Thavorn, Kednapa; Ramsay, Timothy O; Roberge, Guillaume; Grant, Alyssa; Mai, Vicky; de Wit, Kerstin; Le Gal, Grégoire; Wan, Tony; Rodger, Marc A; Douketis, James D; Ostrowski, Margaret

Environmental Sustainability in Hospitals: A Series of Scoping Reviews -$100,000

• Principal Investigator(s): Kanji, Salmaan; Tricco, Andrea C; Moloo, Husein; Hutton, Brian
• Co-Investigator(s): Lunny, Carole A; Kuo, Alex; Sajwani, Shellyza; Kyeremanteng, Kwadwo; Thabet, Pierre; Forster, Alan J

Non-hOme Transition rIsk Following surgerY (NOTIFY) study - $378,676

• Principal Investigator(s): McIsaac, Daniel I; Kidd, Gurlavine D; Wijeysundera, Duminda N; Flexman, Alana M; Garland, Allan; Hallet, Julie; Wong, Camilla L; Kobewka, Daniel M; Van Walraven, Carl
• Co-Investigator(s): Khadaroo, Rachel; Hladkowicz, Emily; Lee, Susan M; Lalu, Manoj M; Mbadjeu Hondjeu, Arnaud Romeo; Ladha, Karim; Aucoin, Sylvie D; Boet, Sylvain; Bryson, Gregory L; Carrier, François M; Chesney, Tyler; Forster, Alan J; Abdellatif, Soha; Alkadri, Jamal; Ma, Grace; Gagné, Sylvain; Grudzinski, Alexa L; Holroyd-Leduc, Jayna M; Huang, Allen R; Jerath, Angela; Moloo, Husein; Power, Barbara E; McIsaac, Sarah; Auer, Rebecca Ann C; Beattie, William S; Mayson, Kelly V; Talarico, Robert F; Huang, Shirley; Reich, Krista; Martel, Guillaume; Lavallée, Luke T; Ke, Xue Chen; Beckerleg, Weiwei; Taljaard, Monica; Sutherland, Jason M; Tanuseputro, Peter; Backman, Chantal; Breau, Rodney H
• ET AL.

PREPARE for Cancer Surgery Trial: multimodal PReoperative Exercise to decrease PostoperAtive disability, cancer RecurrencE and mortality in older people with frailty - $100,000

• Principal Investigator(s): McIsaac, Daniel I; Khadaroo, Rachel; Gillis, Chelsia A; Muscedere, John; Taljaard, Monica; Kidd, Gurlavine D; Fergusson, Dean A; Eskander, Antoine
• Co-Investigator(s): Ladha, Karim; Huang, Allen R; Bryson, Gregory L; Serrano, Pablo E; Scheede-Bergdahl, Celena; Saha, Tarit; Nantel, Julie; Nagpal, Sudhir; Lavallée, Luke T; Lalu, Manoj M; Hladkowicz, Emily; Gagné, Sylvain; Forster, Alan J; Boet, Sylvain; Power, Barbara E; Moloo, Husein; Wijeysundera, Duminda N; Van Walraven, Carl; Lee, Susan M; Holroyd-Leduc, Jayna M; Breau, Rodney H; Nelson, Gregg; Ouyang, Yongdong; Vickers, Michael M; Chesney, Tyler; Johnson, Ana; Ong, Michael; Thavorn, Kednapa

Feasibility of Advance Consent for ParticipaTION in Acute Stroke Trials (ACTION) - $126,225

• Principal Investigator(s): Shamy, Michel C; Dowlatshahi, Dariush
• Co-Investigator(s): Lindsay, Mary Patrice; Hill, Michael D; Swartz, Richard; Fahed, Robert; Nicholls, Stuart G; Gocan, Sophia; Shepherd, Victoria; Poppe, Alexandre Y; Perry, Jeffrey J; Menon, Bijoy K; Brehaut, Jamie C

A randomized trial of anti-arrhythmic agents to improve management of emergency department patients with acute atrial fibrillation - $302,176

• Principal Investigator(s): Stiell, Ian G
• Co-Investigator(s): Macle, Laurent; Perry, Jeffrey J; Nicholls, Stuart G; Eagles, Debra; Yadav, Krishan; Parkash, Ratika; Taljaard, Monica; Mercier, Eric; Morris, Judy M; Vadeboncoeur, Alain; Archambault, Patrick; Birnie, David H; McRae, Andrew D; Scheuermeyer, Frank; Hohl, Corinne M; Campbell, Samuel G; Sivilotti, Marco L; Emond, Marcel; Cournoyer, Alexis; Thavorn, Kednapa

Therapeutic potential of stem cells in lung injury- $971,550

• Principal Investigator(s): Thébaud, Bernard

Reducing inequitable differences in health outcomes in the treatment of arthritis -$416,924

• Principal Investigator(s): Tugwell, Peter S; Welch, Vivian A
• Co-Investigator(s): Barber, Claire E; Hazlewood, Glen S; Toupin April, Karine; Tomlinson, Eve; Shea, Beverley J; Maxwell, Lara; Magwood, Olivia; Li, Linda C; Lee, Alex Young Soo; Dewidar, Omar K; Darzi, Andrea; Barnabe, Cheryl C; Ali, Shehzad; Petkovic, Jennifer

EPIphANy (Evaluation of Pharmacological Interactions with Anticoagulants in caNcer patients) program - prostate cancer cohort - $164,476

• Principal Investigator(s): Wang, Tzu-Fei; Sood, Manish M
• Co-Investigator(s): Carrier, Marc; Bossé, Dominick; Ravani, Pietro; Hawken, Steven; Tangri, Navdeep; Tanuseputro, Peter

High-dose cephalexin for cellulitis (HI-DOCC): a randomized controlled trial - $382,500

• Principal Investigator(s): Yadav, Krishan; Stiell, Ian G; Perry, Jeffrey J; Emond, Marcel; Taljaard, Monica; Eagles, Debra
• Co-Investigator(s): Borgundvaag, Bjug; Campbell, Samuel G; de Wit, Kerstin; Suh, Kathryn N; McRae, Andrew D; Mercier, Eric; Yan, Justin; Ohle, Robert; Nicholls, Stuart G; Corrales-Medina, Vicente F; Hohl, Corinne M; Savage, David; Daoust, Raoul; MacFadden, Derek R; Thavorn, Kednapa; Zheng, Bo; Blanchard, Pierre-Gilles

STOPNET - A Randomized Study of Cessation of Somatostatin Analogues after Peptide Receptor Radionuclide Therapy in Mid and Hind Gut Neuroendocrine Tumours - $260,101

• Principal Investigator(s): Loree, Jonathan M; O'Callaghan, Christopher J
• Co-Investigator(s): Asmis, Timothy R; Barker, Daniel; Burge, matthew; Goodwin, Rachel A; Laidley, David; Little, Marie-Terese; Rayson, Daniel; Singh, Simron; Solar Vasconcelos, Joao Paulo; Tu, Dongsheng; Wyld, David
• Note: this grant is administered at the University of British Columbia